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Ian O. Ellis
Researcher at University of Nottingham
Publications - 1071
Citations - 84964
Ian O. Ellis is an academic researcher from University of Nottingham. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 126, co-authored 1051 publications receiving 75435 citations. Previous affiliations of Ian O. Ellis include Mansoura University & Curie Institute.
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Journal ArticleDOI
Relationship Between Quantitative Estrogen and Progesterone Receptor Expression and Human Epidermal Growth Factor Receptor 2 (HER-2) Status With Recurrence in the Arimidex, Tamoxifen, Alone or in Combination Trial
Mitch Dowsett,Craig Allred,Jill Knox,Emma Quinn,Janine Salter,Chris Wale,Jack Cuzick,Joan Houghton,Norman R. Williams,Elizabeth Mallon,H Bishop,Ian O. Ellis,Denis Larsimont,Hironobu Sasano,Pauline J Carder,Antonio Llombart Cussac,F Knox,Valerie Speirs,John F. Forbes,Aman U. Buzdar +19 more
TL;DR: Quantitative expression of ER and PgR and HER-2 status did not identify patients with differential relative benefit from anastrozole over tamoxifen: TTR was longer for anast rozole than for tamoxIFen in all molecular subgroups.
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Histological grading of breast carcinomas: A study of interobserver agreement
Peter Robbins,Peter Robbins,Sarah E Pinder,Sarah E Pinder,N H de Klerk,N H de Klerk,Hugh Dawkins,Hugh Dawkins,Jennet Harvey,Jennet Harvey,Greg Sterrett,Greg Sterrett,Ian O. Ellis,Ian O. Ellis,C. W. Elston,C. W. Elston +15 more
TL;DR: The similar levels of agreement in training and test sets suggest that reasonable results can be achieved without direct training by expert groups, suggesting that experience and precise grading guidelines are of value.
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Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial
Charlotte E. Coles,Clare Griffin,Anna M. Kirby,Jenny Titley,R.K. Agrawal,Abdulla Alhasso,I.S. Bhattacharya,A.M. Brunt,Laura Ciurlionis,Charlie Chan,Ellen M. Donovan,M. Emson,Adrian Harnett,Joanne S Haviland,Penelope Hopwood,Monica L Jefford,Ronald Kaggwa,Elinor J. Sawyer,Isabel Syndikus,Y. Tsang,Duncan Wheatley,Maggie Wilcox,John Yarnold,Judith M Bliss,Wail Al Sarakbi,Sarah Barber,Gillian C. Barnett,Peter Bliss,John Dewar,David J. Eaton,S. Ebbs,Ian O. Ellis,Philip M. Evans,Emma J. Harris,Hayley James,Cliona C. Kirwan,Julie Kirk,Helen Mayles,Anne McIntyre,J. Mills,A. Poynter,Elena Provenzano,Christine Rawlings,Mark Sculpher,Georges Sumo,M. Sydenham,Andrew Tutt,N. Twyman,K Venables,Anna Winship,John Winstanley,Gordon C. Wishart,Alastair M. Thompson +52 more
TL;DR: It is hypothesised that partial-breast radiotherapy restricted to the vicinity of the original tumour in women at lower than average risk of local relapse will improve the balance of beneficial versus adverse effects compared with whole-breasts radiotherapy.
Journal ArticleDOI
The shaping and functional consequences of the microRNA landscape in breast cancer
Heidi Dvinge,Anna Git,Stefan Gräf,Stefan Gräf,Mali Salmon-Divon,Mali Salmon-Divon,Christina Curtis,Andrea Sottoriva,Yongjun Zhao,Yongjun Zhao,Martin Hirst,Martin Hirst,Javier Armisen,Eric A. Miska,Suet-Feung Chin,Elena Provenzano,Gulisa Turashvili,Andrew R. Green,Ian O. Ellis,Samuel Aparicio,Carlos Caldas +20 more
TL;DR: It is found that miRNAs act as modulators of mRNA–mRNA interactions rather than as on–off molecular switches, demonstrating such an important modulatory role for miRNAAs in the biology of CNA-devoid breast cancers, a common subtype in which the immune response is prominent.
Journal ArticleDOI
The 2019 World Health Organization classification of tumours of the breast.
Puay Hoon Tan,Ian O. Ellis,Kimberly H. Allison,Edi Brogi,Stephen B. Fox,Sunil R. Lakhani,Alexander J. Lazar,Elizabeth A. Morris,Aysegul Sahin,Roberto Salgado,Anna Sapino,Hironobu Sasano,Stuart J. Schnitt,Christos Sotiriou,Paul J. van Diest,Valerie A. White,Dilani Lokuhetty,Ian A. Cree +17 more
TL;DR: The newly published World Health Organization (WHO) Classification of Tumours of the breast features significant changes compared to earlier editions, and this review outlines the major changes.