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Ian Phillips
Researcher at University College London
Publications - 263
Citations - 12780
Ian Phillips is an academic researcher from University College London. The author has contributed to research in topics: Gene & Complementary DNA. The author has an hindex of 55, co-authored 260 publications receiving 12208 citations. Previous affiliations of Ian Phillips include University of London & Queen Mary University of London.
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Journal ArticleDOI
Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.
TL;DR: The expression of genes encoding flavin-containing monooxygenases (FMOs) 1, 3, 4, and 5 and cytochromes P450 (CYPs) 2A6, 2B6, and 3A4 was determined by RNase protection as mentioned in this paper.
Journal ArticleDOI
Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics.
TL;DR: Differences in enhancer half-site spacing may influence the efficiency of interactions between the receptor and the transcription machinery and hence form the basis for the differential induction of CYP2B1 and CYP3A1 in response to barbiturates and synthetic steroids.
BookDOI
Cytochrome P450 protocols
TL;DR: Cytochrome P450 Nomenclature, 2004 David R. Nelson Spectral Analyses of Cytochromes P450 John B. Schenkman and Ingela Jansson Establishment of Functional Human CytochromeP450 Monooxygenase Systems in Escherichia coli Michael P. Pritchard and Lesley McLaughlin.
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Antibacterial Activity of Cefamandole, a New Cephalosporin Antibiotic, Compared with that of Cephaloridine, Cephalothin, and Cephalexin
TL;DR: Cefamandole was the most active of the four agents against Haemophilus species and gram-negative bacilli susceptible to cephalosporins, but had no useful activity against Pseudomonas species.
Journal ArticleDOI
The comparative in-vitro activity of eight newer quinolones and nalidixic acid
Anna King,Ian Phillips +1 more
TL;DR: The 4-quinolones were all highly active against most isolates of Enterobacteriaceae, including nalidixic acid-resistant strains, and against the anaerobic bacteria CI-934 was again the most active compound, particularly against the Gram-positive an aerobic cocci.