Ifat Klein

TL;DR: The findings suggest that the profound antioxidant capacity of saliva secreted from parotid glands is related either to the different physiological demands related to eating, to oral integrity maintenance, or to the high content of deleterious redox-active transitional metal ions present in parotsid saliva.

TL;DR: It is concluded that the loss of salivary enzyme activities may be due to various agents in the CS that affect the enzyme activities via different mechanisms.

TL;DR: The results may be of great clinical importance, as heavy smokers smoke 20 cigarettes or more on a daily basis, most of the time the oral epithelium of heavy smokers is essentially unprotected by OPO against the deleterious effects of thiocyanate ions and hydroxyl radicals produced by unremoved hydrogen peroxide in the presence of the salivary redox-active metal ions.

TL;DR: Salivary LDH may be evaluated for possible oral mucosal pathologies in a manner similar to that used for evaluating other tissue pathologies--such as those in heart, muscle, or liver--that can be detected in plasma.

TL;DR: The results show that hydrogen cyanide is likely to be the species in CS responsible for loss of salivary OPO activity, and this may represent a contributory mechanism for CS-related compromises in antimicrobial defenses in the aerodigestive tract.