scispace - formally typeset
I

Ignacio G. Camarillo

Researcher at Purdue University

Publications -  58
Citations -  919

Ignacio G. Camarillo is an academic researcher from Purdue University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 15, co-authored 54 publications receiving 778 citations. Previous affiliations of Ignacio G. Camarillo include University of California, Santa Cruz & Wayne State University.

Papers
More filters
Journal ArticleDOI

Leptin–STAT3–G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression

TL;DR: The results show how targeting STAT3-G9a signaling regulates CSC plasticity during obesity-related breast cancer progression, suggesting a novel therapeutic paradigm to suppress CSC pools and limit breast malignancy.
Journal ArticleDOI

Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.

TL;DR: The role for epigenetics in regulation of NOTCH signaling in breast cancer may constitute a common mechanism of activation of oncogenic signals and this study provides support for epigenetic-targeting strategies in anticancer approaches.
Journal ArticleDOI

Leptin-regulated gene expression in MCF-7 breast cancer cells: mechanistic insights into leptin-regulated mammary tumor growth and progression.

TL;DR: The identification of leptin-regulated genes in hormone-responsive Michigan Cancer Foundation-7 (MCF-7) human breast cancer cells is described to provide mechanistic links into the relationship between obesity and breast cancer incidence and morbidity.
Journal ArticleDOI

Nonlinear optical imaging to evaluate the impact of obesity on mammary gland and tumor stroma.

TL;DR: Nonlinear optical imaging technologies are combined with an early-onset diet-induced obesity breast cancer animal model to evaluate the impact of obesity on the composition of mammary gland and tumor stroma to provide the first imaging evidence that supports the relationship between obesity and breast cancer risk.