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Imen Miladi
Researcher at Tunis University
Publications - 15
Citations - 955
Imen Miladi is an academic researcher from Tunis University. The author has contributed to research in topics: Biodistribution & Colloidal gold. The author has an hindex of 12, co-authored 15 publications receiving 871 citations. Previous affiliations of Imen Miladi include University of Lyon & Claude Bernard University Lyon 1.
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Toward an image-guided microbeam radiation therapy using gadolinium-based nanoparticles.
Géraldine Le Duc,Imen Miladi,Christophe Alric,Pierre Mowat,Elke Bräuer-Krisch,Audrey Bouchet,Enam A. Khalil,Claire Billotey,Marc Janier,François Lux,Thierry Epicier,Pascal Perriat,Stéphane Roux,Stéphane Roux,Olivier Tillement +14 more
TL;DR: GBNs exhibit an interesting potential for image-guided radiotherapy since the radiosensitizing effect of GBNs can be activated by X-ray microbeams when the gadolinium content is enough in the tumor and low in the surrounding healthy tissue.
Journal ArticleDOI
The biodistribution of gold nanoparticles designed for renal clearance
Christophe Alric,Imen Miladi,David Kryza,Jacqueline Taleb,François Lux,Rana Bazzi,Claire Billotey,Marc Janier,Pascal Perriat,Stéphane Roux,Olivier Tillement +10 more
TL;DR: The successful immobilization of radioelements in the DTDTPA shell renders possible the follow up of Au@D TDTPA by scintigraphy which showed that Au@ dithiolated polyaminocarboxylate nanoparticles exhibit a safe behaviour after intravenous injection to healthy rats.
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The in vivo radiosensitizing effect of gold nanoparticles based MRI contrast agents
Imen Miladi,Christophe Alric,Sandrine Dufort,Pierre Mowat,Aurélie Dutour,Céline A. Mandon,Gautier Laurent,Elke Bräuer-Krisch,Nirmitha I. Herath,Jean-Luc Coll,Marie Dutreix,François Lux,Rana Bazzi,Claire Billotey,Marc Janier,Pascal Perriat,Géraldine Le Duc,Stéphane Roux,Olivier Tillement +18 more
TL;DR: Comet assays and in vivo experiments suggest that these particles appear well suited for improving the selectivity of the radiotherapy, and the increase in the lifespan of tumor bearing rats is more important when the irradiation is performed after the injection of the gold nanoparticles.
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Biodistribution study of nanometric hybrid gadolinium oxide particles as a multimodal SPECT/MR/optical imaging and theragnostic agent.
David Kryza,Jacqueline Taleb,Marc Janier,Laurence Marmuse,Imen Miladi,Pauline Bonazza,Cédric Louis,Pascal Perriat,Stéphane Roux,Olivier Tillement,Claire Billotey +10 more
TL;DR: It is demonstrated that Gado-6Si-NP display optimal biodistribution properties, enabling them to be developed as multimodal agents for in vivo imaging and theragnostics, especially in oncological applications.
Journal ArticleDOI
Dendronized iron oxide nanoparticles for multimodal imaging.
Giuseppe Lamanna,Marie Kueny-Stotz,Hind Mamlouk-Chaouachi,Cynthia Ghobril,Brice Basly,Annabelle Bertin,Imen Miladi,Claire Billotey,Geneviève Pourroy,Sylvie Begin-Colin,Delphine Felder-Flesch +10 more
TL;DR: Magnetic resonance and fluorescence imaging are demonstrated to be simultaneously possible using such versatile superparamagnetic iron oxide nanocrystals covered by a dendritic shell displaying either carboxylate or ammonium groups at their periphery which could be further labelled with a fluorescent dye.