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Institut national des sciences Appliquées de Lyon

EducationLyon, France
About: Institut national des sciences Appliquées de Lyon is a education organization based out in Lyon, France. It is known for research contribution in the topics: Finite element method & Silicon. The organization has 6533 authors who have published 9942 publications receiving 211993 citations.

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Journal ArticleDOI
Stephen Richards1, Richard A. Gibbs1, Nicole M. Gerardo2, Nancy A. Moran3  +220 moreInstitutions (58)
TL;DR: The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.
Abstract: Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.

1,271 citations

Journal ArticleDOI
TL;DR: This exhibition celebrates the centenary of the establishment of the University of Lyon with a celebration of the 100th anniversary of the birth of Jean-Bertrand Aristide Dejerine.
Abstract: Laboratoire de Génie Enzymatique et Biomoléculaire, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, 43 Boulevard du 11 Novembre 1918, Villeurbanne F-69622, France, UMR5246, Centre National de La Recherche Scientifque, Villeurbanne F-69622, France, Université de Lyon, Lyon F-69622, France, Université Lyon 1, Lyon F-69622, France, Institut National des Sciences Appliquées de Lyon, EÄ cole d’Ingénieurs, Villeurbanne F-69621, France, and EÄ cole Supérieure Chimie Physique EÄ lectronique de Lyon, Villeurbanne F-69616, France

1,123 citations

Journal ArticleDOI
01 Dec 1984-Wear
TL;DR: The third-body approach highlights the many features which are common to different types of materials in different kinds of rubbing contacts, and suggests that a picture which is globally coherent from a mechanical point of view, in that it obeys as a first step the laws of equilibrium and continuity, can be presented.

866 citations

Journal ArticleDOI
TL;DR: Isocyanate, and Non-isocyanates Polyurethane Etienne Delebecq, Jean-Pierre Pascault,‡,§ Bernard Boutevin,† and Franco̧is Ganachaud*,† are cited.
Abstract: Isocyanate, and Non-isocyanate Polyurethane Etienne Delebecq,† Jean-Pierre Pascault,‡,§ Bernard Boutevin,† and Franco̧is Ganachaud*,†,‡,§ †Institut Charles Gerhardt, UMR 5253 CNRS, Ingeńierie et Architectures Macromolećulaires, Ecole Nationale Supeŕieure de Chimie de Montpellier, 8 rue de l’ećole normale, 34296 Montpellier, Cedex 05, France ‡INSA-Lyon, IMP, UMR5223, F-69621, Villeurbanne, France Universite ́ de Lyon, F-69622, Lyon, France

839 citations

Journal ArticleDOI
TL;DR: This paper aims to provide a history of the use of glass in the construction of buildings in Montpellier and its applications in the 21st Century.
Abstract: Reḿi Auvergne,† Sylvain Caillol,† Ghislain David,*,† Bernard Boutevin,† and Jean-Pierre Pascault‡,§ †Institut Charles Gerhardt UMR CNRS 5253 Laboratoire Ingeńierie et Architecture Macromolećulaire, Ecole Nationale Supeŕieure de Chimie de Montpellier, 8 rue de l’Ecole Normale, 34296 Montpellier Cedex 05, France ‡INSA-Lyon, IMP, UMR5223, F-69621, Villeurbanne, France Universite ́ de Lyon, F-69622, Lyon, France

790 citations


Showing all 6570 results

Eric Christian Chabert128105782280
George C Patton11857894634
Alain Dufresne11135845904
Emmanuel Mignot10361140891
Olivier Bernard9679037878
Emmanuel P. Giannelis8838738528
Hubert Vidal8333325594
Robert J Henry7267623731
Hongping He6842116531
Mischa Dohler6835519614
Denis Fouque6137417101
Jan D'hooge5954413729
Françoise Peyrin583919819
Wolfgang Ludwig5824412714
Eric Maire5738014148
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