Ina Baumann

TL;DR: Differences in enhancer efficiency in different cell lines are interpreted to indicate differences in the activity of a trans-acting factor.

TL;DR: The intracellular protozoan parasite Theileria parva is identified and characterized in infected cells the transcriptional activator, NF-kappa B, whose recognition motifs have been identified in several gene enhancers important for lymphocyte-specific gene expression and it is proposed that high levels of activated NF- kappa B are maintained by the presence of the parasite in infected T cells.

TL;DR: It is demonstrated that all members of the NF-κB/Rel family of proteins translocate to the nucleus of infected cells by western blot, and several agents known to inhibit a wide range of NF-σκB activation pathways had no inhibitory effect on the activation of DNA binding in TpM(803) T cells.

TL;DR: It is shown that a persuasive clone isolated can still be a false positive (spontaneous revertant) and that an extremely laborious approach may lead into a dead end.