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Inge Betz
Researcher at Katholieke Universiteit Leuven
Publications - 3
Citations - 1129
Inge Betz is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Survivin & Inhibitor of apoptosis. The author has an hindex of 3, co-authored 3 publications receiving 852 citations.
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Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
Katrien De Bock,Maria Georgiadou,Sandra Schoors,Anna Kuchnio,Brian W. Wong,Anna Rita Cantelmo,Annelies Quaegebeur,Bart Ghesquière,Sandra Cauwenberghs,Guy Eelen,Li-Kun Phng,Inge Betz,Bieke Tembuyser,Katleen Brepoels,Jonathan Welti,Ilse Geudens,Inmaculada Segura,Bert Cruys,Franscesco Bifari,Ilaria Decimo,Raquel Blanco,Sabine Wyns,Jeroen Vangindertael,Susana Rocha,Russel T Collins,Sebastian Munck,Dirk Daelemans,Hiromi Imamura,Roland Devlieger,Mark H. Rider,Paul P. Van Veldhoven,Frans Schuit,Ramon Bartrons,Johan Hofkens,Peter Fraisl,Sucheta Telang,Ralph J. DeBerardinis,Luc Schoonjans,Stefan Vinckier,Jason Chesney,Holger Gerhardt,Holger Gerhardt,Mieke Dewerchin,Peter Carmeliet +43 more
TL;DR: It is shown that ECs relied on glycolysis rather than on oxidative phosphorylation for ATP production and that loss of the gly colytic activator PFKFB3 in ECs impaired vessel formation.
Journal ArticleDOI
Role of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis
Mieke Delvaeye,Astrid De Vriese,Femke Zwerts,Inge Betz,Michaël Moons,Monica Autiero,Edward M. Conway +6 more
TL;DR: These properties of survivin, which are consistent with those identified in mice, indicate that its functions are highly conserved across species, and point to the value of the zebrafish model in understanding the role of this IAP in the pathogenesis of human disease, and for exploring its potential as a therapeutic target.
Journal ArticleDOI
Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure
TL;DR: It is shown that survivin is required to protect the kidney from apoptosis, to suppress renal expression of p53, and to ameliorate renal dysfunction in two models of ARF.