Inger-Lise Hansteen

TL;DR: An increased level of chromosome breakage appears to be a relevant biomarker of future cancer risk in peripheral blood lymphocytes, according to an ongoing Nordic cohort study of cancer incidence.

TL;DR: The effects of nickel ions on fetal human kidney cortex explants were studied and Immortalized cell lines were established and demonstrated to be of human epithelial origin.

TL;DR: A pooled analysis of the updated cohorts will now be performed, allowing a more solid evaluation of cytogenetic biomarkers in healthy subjects, and the importance of potential effect modifiers, such as gender, age at testing, and time since testing, will be evaluated using Poisson regression models.

TL;DR: It is concluded that chromosomes 1, 14, 21, and 22 may be involved in the preclinical stage of development of asbestos-induced mesothelioma, whereas the later chromosomal changes may be related to progression of the tumor.

TL;DR: The combined action of a chemical carcinogen and v‐Ha‐ras oncogene resulted in fully transformed human kidney epithelial cells, consistent with a stepwise progression of human epithelial cell transformation.