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Ingrid J.W. Elbers
Publications - 6
Citations - 623
Ingrid J.W. Elbers is an academic researcher. The author has contributed to research in topics: Plantibody & Glycoprotein. The author has an hindex of 3, co-authored 3 publications receiving 601 citations.
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Journal ArticleDOI
Galactose-extended glycans of antibodies produced by transgenic plants.
Hans Bakker,Muriel Bardor,Jos Molthoff,Véronique Gomord,Ingrid J.W. Elbers,Lucas H. Stevens,Wilco Jordi,Arjen Lommen,Loïc Faye,Patrice Lerouge,Dirk Bosch +10 more
TL;DR: The results indicate that the human β1,4-galactosyltransferase is fully functional and localizes correctly in the Golgi apparatus, a major step in the in planta engineering of the N-glycosylation of recombinant antibodies.
Journal ArticleDOI
Effect of Climate Conditions and Plant Developmental Stage on the Stability of Antibodies Expressed in Transgenic Tobacco
Lucas H. Stevens,Geert Stoopen,Ingrid J.W. Elbers,Jos Molthoff,Hans Bakker,Arjen Lommen,Dirk Bosch,Wilco Jordi +7 more
TL;DR: The results of this study indicate that proteolytic degradation during plant development can be an important factor affecting yield and homogeneity of heterologous protein produced by transgenic plants.
Journal ArticleDOI
Influence of growth conditions and developmental stage on N-glycan heterogeneity of transgenic immunoglobulin G and endogenous proteins in tobacco leaves
Ingrid J.W. Elbers,Geert Stoopen,Hans Bakker,Lucas H. Stevens,Muriel Bardor,Jos Molthoff,Wilco Jordi,Dirk Bosch,Arjen Lommen +8 more
TL;DR: Senescence was shown to affect the glycosylation profile of endogenous proteins and major differences were observed between glycan structures on endogenous proteins versus those on antibodies, probably to be attributed to their subcellular localization.
Journal ArticleDOI
Proficiency and Interlaboratory Variability in the Determination of Phthalate and DINCH Biomarkers in Human Urine: Results from the HBM4EU Project
Hans G.J. Mol,Ingrid J.W. Elbers,Claudia Pälmke,Daniel Bury,Thomas Göen,Marta Esteban-López,Stefanie Nübler,Vincent Vaccher,Jean-Philippe Antignac,Darina Dvorakova,Jana Hajslova,Amrit Kaur Sakhi,Cathrine Thomsen,Katrin Vorkamp,Argelia Castaño,Holger M. Koch +15 more
TL;DR: A quality assurance/quality control program was implemented in the framework of the EU project HBM4EU to assess and improve the comparability of biomarker analysis and to build a network of competent laboratories able to generate comparable and accurate HBM data for phthalate and DINCH biomarkers in 14 EU countries.
ReportDOI
Proficiency test for pyrrolizidine alkaloidsin food matrices : EURLPT-MP07 (2022)
TL;DR: A proficiency test for the quantitative analysis of pyrrolizidine alkaloids (PAs) in the food matrices black tea and the culinary herb marjoram was organised by the European Union Reference Laboratory for mycotoxins & plant toxins in food and feed (EURL-MP) between December 2021 and March 2022 as mentioned in this paper .