J
Jos Molthoff
Researcher at Wageningen University and Research Centre
Publications - 17
Citations - 1997
Jos Molthoff is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Gene & Plantibody. The author has an hindex of 14, co-authored 16 publications receiving 1800 citations.
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Journal ArticleDOI
Galactose-extended glycans of antibodies produced by transgenic plants.
Hans Bakker,Muriel Bardor,Jos Molthoff,Véronique Gomord,Ingrid J.W. Elbers,Lucas H. Stevens,Wilco Jordi,Arjen Lommen,Loïc Faye,Patrice Lerouge,Dirk Bosch +10 more
TL;DR: The results indicate that the human β1,4-galactosyltransferase is fully functional and localizes correctly in the Golgi apparatus, a major step in the in planta engineering of the N-glycosylation of recombinant antibodies.
Journal ArticleDOI
Biochemical and Molecular Analysis of Pink Tomatoes: Deregulated Expression of the Gene Encoding Transcription Factor SlMYB12 Leads to Pink Tomato Fruit Color
Ana-Rosa Ballester,Jos Molthoff,Ric C. H. de Vos,Bas te Lintel Hekkert,Diego Orzaez,Josefina-Patricia Fernandez-Moreno,Pasquale Tripodi,Silvana Grandillo,Cathie Martin,Jos Heldens,Marieke Ykema,Antonio Granell,Arnaud G. Bovy +12 more
TL;DR: In this article, an introgression analysis of an IL population derived from a cross between Solanum lycopersicum 'Moneyberg' and the wild species Solanian chmielewskii revealed three ILs with a pink fruit color.
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RNA interference silencing of chalcone synthase, the first step in the flavonoid biosynthesis pathway, leads to parthenocarpic tomato fruits.
Elio Schijlen,C.H. Ric de Vos,Stefan Martens,Harry Jonker,Faye M. Rosin,Jos Molthoff,Yury Tikunov,Gerco C. Angenent,Arjen J. van Tunen,Arnaud G. Bovy +9 more
TL;DR: A novel strategy to obtain parthenocarpic tomatoes by down-regulation of the flavonoid biosynthesis pathway using RNA interference (RNAi)-mediated suppression of chalcone synthase (CHS), the first gene in the Flavonoid pathway is proposed.
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The Impact of the Absence of Aliphatic Glucosinolates on Insect Herbivory in Arabidopsis
Jules Beekwilder,W. van Leeuwen,Nicole M. van Dam,Monica Bertossi,Valentina De Grandi,Luca Mizzi,Mikhail Soloviev,László Szabados,Jos Molthoff,Bert Schipper,Hans Verbocht,Ric C. H. de Vos,Piero Morandini,Mark G. M. Aarts,Arnaud G. Bovy +14 more
TL;DR: It is shown that MYB28 and MYB29 are partially redundant, but in the absence of both, the synthesis of all aliphatic glucosinolates is blocked, and since the myb28myb29 double mutant is the first Arabidopsis genotype without any aliphatics, its relevance to herbivory by larvae of the lepidopteran insect Mamestra brassicae is established.
Journal ArticleDOI
Pathway engineering for healthy phytochemicals leading to the production of novel flavonoids in tomato fruit
Elio Schijlen,C.H. Ric de Vos,Harry Jonker,Hetty C. van den Broeck,Jos Molthoff,Arjen J. van Tunen,Stefan Martens,Arnaud G. Bovy +7 more
TL;DR: The results on genetic engineering of flavonoids in tomato fruit demonstrate the possibilities to change the levels and composition of health-related polyphenols in a crop plant and provide more insight in the genetic and biochemical regulation of the flavonoid pathway within this worldwide important vegetable.