Ira M. Longini

TL;DR: The results suggest that early detection, hand washing, self-isolation, and household quarantine will likely be more effective than travel restrictions at mitigating this pandemic, and sustained 90% travel restrictions to and from mainland China only modestly affect the epidemic trajectory unless combined with a 50% or higher reduction of transmission in the community.

TL;DR: Investigation of the effectiveness of targeted antiviral prophylaxis, quarantine, and pre-vaccination in containing an emerging influenza strain at the source showed that a prepared response with targeted antivirals would have a high probability of containing the disease.

TL;DR: A large-scale stochastic simulation model is introduced and used to investigate the spread of a pandemic strain of influenza virus through the U.S. population and suggests that the rapid production and distribution of vaccines could significantly slow disease spread and limit the number ill to <10% of the population, particularly if children are preferentially vaccinated.

TL;DR: The evidence from all 117 clusters showed that no cases of Ebola virus disease occurred 10 days or more after randomisation among all immediately vaccinated contacts and contacts of contacts of recently confirmed cases in Guinea, west Africa.

TL;DR: Targeted antiviral prophylaxis has potential as an effective measure for containing influenza until adequate quantities of vaccine are available and is nearly as effective as vaccinating 80% of the population.