I
Irene E. Zohn
Researcher at Children's National Medical Center
Publications - 35
Citations - 1530
Irene E. Zohn is an academic researcher from Children's National Medical Center. The author has contributed to research in topics: Neural tube & Neurulation. The author has an hindex of 16, co-authored 33 publications receiving 1353 citations. Previous affiliations of Irene E. Zohn include Howard Hughes Medical Institute & University of Colorado Denver.
Papers
More filters
Journal ArticleDOI
The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation
Anita Becker-Heck,Irene E. Zohn,Irene E. Zohn,Noriko Okabe,Andrew Pollock,Kari Baker Lenhart,Jessica Sullivan-Brown,Jason C. McSheene,Niki T. Loges,Heike Olbrich,Karsten Haeffner,Manfred Fliegauf,Judith Horvath,Richard Reinhardt,Kim G. Nielsen,June K. Marthin,Gyorgy Baktai,Kathryn V. Anderson,Robert Geisler,Robert Geisler,Lee Niswander,Heymut Omran,Rebecca D. Burdine +22 more
TL;DR: An uncharacterized coiled-coil domain containing a protein, CCDC40, essential for correct left-right patterning in mouse, zebrafish and human is identified.
Journal ArticleDOI
p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.
TL;DR: It is demonstrated that p38 MAP kinase and a p38-interacting protein (p38IP) are critically required for downregulation of E-cadherin during gastrulation and p38IP binds directly to p38 and is required for p38 activation in vivo.
Journal ArticleDOI
Iron depletion limits intracellular bacterial growth in macrophages.
Prasad N. Paradkar,Ivana De Domenico,Nina Durchfort,Irene E. Zohn,Jerry Kaplan,Diane M. Ward +5 more
TL;DR: It is demonstrated in vitro that the intracellular growth of Chlamydia psittaci, trachomatis, and Legionella pneumophila is regulated by the levels of intrACEllular iron.
Journal ArticleDOI
The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease
Irene E. Zohn,Ivana De Domenico,Andrew Pollock,Diane M. Ward,Jessica F. Goodman,Xiayun Liang,Amaru J. Sanchez,Lee Niswander,Jerry Kaplan +8 more
TL;DR: It is demonstrated that mutations in Fpn resulting in protein mislocalization act in a dominant-negative fashion to cause disease, and the Fpn(ffe) mouse represents the first mouse model of ferroportin disease.
Journal ArticleDOI
The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation
Irene E. Zohn,Anjali A. Sarkar +1 more
TL;DR: The histotrophic mechanisms by which nutrients are delivered to the human embryo during this critical time period of neurulation are reviewed.