J
Jessica Sullivan-Brown
Researcher at Princeton University
Publications - 13
Citations - 1390
Jessica Sullivan-Brown is an academic researcher from Princeton University. The author has contributed to research in topics: Zebrafish & Cilium. The author has an hindex of 9, co-authored 12 publications receiving 1235 citations. Previous affiliations of Jessica Sullivan-Brown include University of North Carolina at Chapel Hill & West Chester University of Pennsylvania.
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Journal ArticleDOI
Apical constriction: a cell shape change that can drive morphogenesis.
Jacob M. Sawyer,Jessica R. Harrell,Gidi Shemer,Jessica Sullivan-Brown,Minna Roh-Johnson,Bob Goldstein +5 more
TL;DR: The diversity of mechanisms of apical constriction, the diversity of roles that apical Constriction plays in development, and the common themes that emerge from comparing systems are reviewed.
Journal ArticleDOI
The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation
Anita Becker-Heck,Irene E. Zohn,Irene E. Zohn,Noriko Okabe,Andrew Pollock,Kari Baker Lenhart,Jessica Sullivan-Brown,Jason C. McSheene,Niki T. Loges,Heike Olbrich,Karsten Haeffner,Manfred Fliegauf,Judith Horvath,Richard Reinhardt,Kim G. Nielsen,June K. Marthin,Gyorgy Baktai,Kathryn V. Anderson,Robert Geisler,Robert Geisler,Lee Niswander,Heymut Omran,Rebecca D. Burdine +22 more
TL;DR: An uncharacterized coiled-coil domain containing a protein, CCDC40, essential for correct left-right patterning in mouse, zebrafish and human is identified.
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SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development
Stefanie Weber,Jaclyn C. Taylor,Paul J.D. Winyard,Kari Baker,Jessica Sullivan-Brown,Raphael Schild,Tanja Knüppel,Aleksandra Zurowska,Alberto Caldas-Alfonso,Mieczysław Litwin,Sevinç Emre,Gian Marco Ghiggeri,Aysin Bakkaloglu,Otto Mehls,Corinne Antignac,Franz Schaefer,Rebecca D. Burdine +16 more
TL;DR: These studies implicate conserved roles for Six2 and Bmp4 in the development of the renal system, which could affect kidney development at multiple stages, leading to the congenital anomalies observed in patients with RHD.
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Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw.
TL;DR: Two alleles of cup are characterized, both of which display defects in organ positioning that resemble human heterotaxia, as well as abnormalities in asymmetric gene expression in the lateral plate mesoderm (LPM) and dorsal diencephalon of the brain.
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Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants
Jessica Sullivan-Brown,Jodi Schottenfeld,Noriko Okabe,Christine L. Hostetter,Fabrizio C. Serluca,Stephan Y. Thiberge,Rebecca D. Burdine +6 more
TL;DR: It is shown that knock-down of polycystic kidney disease 2 (pkd2) specifically causes glomerular cysts and does not affect cilia motility, suggesting multiple mechanisms exist for cyst formation.