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Irene Miguel-Aliaga
Researcher at Imperial College London
Publications - 54
Citations - 3356
Irene Miguel-Aliaga is an academic researcher from Imperial College London. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 24, co-authored 47 publications receiving 2771 citations. Previous affiliations of Irene Miguel-Aliaga include Harvard University & Linköping University.
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The Digestive Tract of Drosophila melanogaster
TL;DR: This review summarizes the knowledge of the Drosophila digestive tract, with an emphasis on the adult midgut and its functional underpinnings.
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Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster
TL;DR: This review summarizes the current knowledge of both the formation and function of the Drosophila melanogaster digestive tract, with a major focus on its main digestive/absorptive portion: the strikingly adaptable adult midgut.
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Enteric Neurons and Systemic Signals Couple Nutritional and Reproductive Status with Intestinal Homeostasis
TL;DR: A quantitative method based on defecation behavior is developed to uncover a central role for the Drosophila intestine in the regulation of nutrient intake, fluid, and ion balance, and identifies a key homeostatic role for autonomic neurons and hormones.
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Neuromuscular defects in a Drosophila survival motor neuron gene mutant
Yick-Bun Chan,Irene Miguel-Aliaga,Chris Franks,Natasha Thomas,Barbara Trülzsch,David B. Sattelle,Kay E. Davies,Marcel van den Heuvel +7 more
TL;DR: A new Drosophila model for SMA is proposed, finding that zygotic smn mutant animals show abnormal motor behavior and that smn gene activity is required in both neurons and muscle to alleviate this phenotype, and proposes a functional role for SMN at the neuromUScular junction in the generation of neuromuscular defects.
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Specification of Neuropeptide Cell Identity by the Integration of Retrograde BMP Signaling and a Combinatorial Transcription Factor Code
TL;DR: An intrinsic transcription factor code integrates with an extrinsic retrograde signal to select a specific neuropeptide identity within peptidergic cells.