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Irina Jovel
Researcher at Karolinska Institutet
Publications - 15
Citations - 335
Irina Jovel is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Plasmodium falciparum & Artemether/lumefantrine. The author has an hindex of 9, co-authored 15 publications receiving 280 citations. Previous affiliations of Irina Jovel include Karolinska University Hospital & Universidad Nacional Autónoma de Honduras.
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Journal ArticleDOI
Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania
Maja Malmberg,Billy Ngasala,Pedro Eduardo Ferreira,Pedro Eduardo Ferreira,Erik Larsson,Irina Jovel,Irina Jovel,Angelica Hjalmarsson,Max Petzold,Zul Premji,José Pedro Gil,José Pedro Gil,José Pedro Gil,Anders Björkman,Andreas Mårtensson +14 more
TL;DR: Temporal trends of established genotypes associated with artemether-lumefantrine tolerance/resistance before and after its deployment as first-line treatment for uncomplicated malaria in Tanzania 2006 are analyzed to represent an early warning sign of impaired future drug efficacy.
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High Rate of Treatment Failures in Nonimmune Travelers Treated With Artemether-Lumefantrine for Uncomplicated Plasmodium falciparum Malaria in Sweden: Retrospective Comparative Analysis of Effectiveness and Case Series.
Klara Sondén,Katja Wyss,Katja Wyss,Irina Jovel,Antero Vieira Silva,Anton Pohanka,Anton Pohanka,Muhammad Asghar,Manijeh Vafa Homann,Lars L. Gustafsson,Lars L. Gustafsson,Urban Hellgren,Urban Hellgren,Anna Färnert,Anna Färnert +14 more
TL;DR: The findings indicate a high rate of symptomatic late treatment failures after 6-dose artemether-lumefantrine regime in nonimmune adults, especially in men, which warrants the need to establish optimal dosing of AL in adults.
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Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.
Irina Jovel,Irina Jovel,Rosa E Mejía,Engels Banegas,Rita Piedade,Rita Piedade,Jackeline Alger,Gustavo Fontecha,Pedro Eduardo Ferreira,Maria Isabel Veiga,Irma G Enamorado,Anders Björkman,Johan Ursing +12 more
TL;DR: It is suggested that chloroquine and sulphadoxine-pyrimethamine should be efficacious for treatment of uncomplicated P. falciparum and P. vivax infections in Honduras, supporting current national treatment guidelines.
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Safety of a Single Low-dose of Primaquine in Addition to Standard Artemether-lumefantrine Regimen for Treatment of Acute Uncomplicated Plasmodium falciparum Malaria in Tanzania.
Richard Mwaiswelo,Billy Ngasala,Irina Jovel,Roland Gosling,Zul Premji,Eugenie Poirot,Bruno P. Mmbando,Anders Björkman,Andreas Mårtensson +8 more
TL;DR: The findings support that the WHO recommendation of adding a single low-dose of PQ to standard AL regimen is safe for the treatment of acute uncomplicated P. falciparum malaria regardless of G6PD status in Tanzania.
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Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras
Ana Cecilia Lopez,Andrés Ortiz,Jorge Coello,Wilfredo Sosa-Ochoa,Rosa Elena Mejia Torres,Engels Banegas,Irina Jovel,Irina Jovel,Gustavo Fontecha +8 more
TL;DR: The results indicate that P. vivax and P. falciparum parasite populations are highly diverse in Honduras despite the low level of transmission.