J
Johan Ursing
Researcher at Karolinska Institutet
Publications - 52
Citations - 2155
Johan Ursing is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Chloroquine & Plasmodium falciparum. The author has an hindex of 22, co-authored 52 publications receiving 1862 citations. Previous affiliations of Johan Ursing include Karolinska University Hospital & Bandim Health Project.
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Journal ArticleDOI
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Elizabeth A. Ashley,Francesca T. Aweeka,Karen I. Barnes,Quique Bassat,Steffen Borrmann,Steffen Borrmann,Prabin Dahal,Prabin Dahal,Tme Davis,Philippe Deloron,Mey Bouth Denis,Abdoulaye Djimde,Jean-François Faucher,Blaise Genton,Blaise Genton,Philippe J Guerin,Kamal Hamed,Eva Maria Hodel,Eva Maria Hodel,Liusheng Huang,Jullien,Harin Karunajeewa,Harin Karunajeewa,Kiechel,Poul-Erik Kofoed,Gilbert Lefèvre,Niklas Lindegardh,Kevin Marsh,Kevin Marsh,Andreas Mårtensson,Mayfong Mayxay,Mayfong Mayxay,Rose McGready,C Moreira,Paul N. Newton,Billy Ngasala,François Nosten,Christian Nsanzabana,Christian Nsanzabana,Sunil Parikh,Ric N. Price,Pascal Ringwald,Lars Rombo,Lars Rombo,Birgit Schramm,Carol Hopkins Sibley,Kasia Stepniewska,Johan Ursing,Michèle van Vugt,Michèle van Vugt,Nicholas J. White,Lesley Workman +51 more
TL;DR: Higher, more frequent, or prolonged dosage regimens should now be evaluated in very young children, particularly if malnourished, and in patients with hyperparasitemia, as well as patients in very low transmission intensity areas with emerging parasite resistance.
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Polymorphisms in Plasmodium falciparum chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine
Meera Venkatesan,Nahla B Gadalla,Kasia Stepniewska,Prabin Dahal,Christian Nsanzabana,Clarissa Moriera,Ric N. Price,Andreas Mårtensson,Philip J. Rosenthal,Grant Dorsey,Colin J. Sutherland,Philippe J Guerin,Timothy M. E. Davis,Didier Menard,Ishag Adam,George O. Ademowo,Cesar Arze,Frederick N. Baliraine,Nicole Berens-Riha,Anders Björkman,Steffen Borrmann,Francesco Checchi,Meghna Desai,Mehul Dhorda,Abdoulaye Djimde,Badria B. El-Sayed,Teferi Eshetu,Frederick Eyase,Catherine O. Falade,Jean-François Faucher,Gabrielle Fröberg,Anastasia Grivoyannis,Sally Hamour,Sandrine Houzé,Jacob D. Johnson,Erasmus Kamugisha,Simon Kariuki,Jean-René Kiechel,Fred Kironde,Fred Kironde,Poul-Erik Kofoed,Jacques Lebras,Maja Malmberg,Maja Malmberg,Leah Mwai,Leah Mwai,Billy Ngasala,François Nosten,Samuel L. Nsobya,Alexis Nzila,Alexis Nzila,Mary C. Oguike,Sabina Dahlström Otienoburu,Bernhards Ogutu,Jean-Bosco Ouédraogo,Patrice Piola,Patrice Piola,Lars Rombo,Birgit Schramm,A. Fabrice Some,Julie Thwing,Johan Ursing,Rina P. M. Wong,Ahmed Zeynudin,Issaka Zongo,Christopher V. Plowe,Carol Hopkins Sibley,Carol Hopkins Sibley +67 more
TL;DR: Monitoring selection and responding to emerging signs of drug resistance are critical tools for preserving efficacy of artemisinin combination therapies; determination of the prevalence of at least pfcrt K76T and pfmdr1 N86Y should now be routine.
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Travel-associated infection presenting in Europe (2008-12): an analysis of EuroTravNet longitudinal, surveillance data, and evaluation of the effect of the pre-travel consultation
Patricia Schlagenhauf,Leisa H. Weld,Abraham Goorhuis,Philippe Gautret,Rainer Weber,Frank von Sonnenburg,Rogelio López-Vélez,Mogens Jensenius,Jakob P. Cramer,Vanessa Field,Silvia Odolini,Effrossyni Gkrania-Klotsas,François Chappuis,Denis Malvy,Perry J.J. van Genderen,Frank P. Mockenhaupt,Stéphane Jauréguiberry,Catherine C. Smith,Nicholas J. Beeching,Johan Ursing,Christophe Rapp,Philippe Parola,Martin P. Grobusch +22 more
TL;DR: Pre-travel consultation was associated with significantly lower proportionate morbidity ratios for P falciparum malaria and also for acute hepatitis and HIV/AIDS and cast doubt on the effectiveness of current strategies to prevent travel-related diarrhoea.
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Genetic diversity among Plasmodium falciparum field isolates in Pakistan measured with PCR genotyping of the merozoite surface protein 1 and 2
Najia Karim Ghanchi,Najia Karim Ghanchi,Andreas Mårtensson,Andreas Mårtensson,Johan Ursing,Sana Jafri,Sándor Bereczky,Rabia Hussain,Mohammad Asim Beg +8 more
TL;DR: The genetic diversity and allelic distribution found in this study is similar to previous reports from India and Southeast Asian countries with low malaria endemicity.
Journal ArticleDOI
Plasmodium falciparum drug resistance phenotype as assessed by patient antimalarial drug levels and its association with pfmdr1 polymorphisms
Maja Malmberg,Pedro Eduardo Ferreira,Joel Tarning,Joel Tarning,Johan Ursing,Billy Ngasala,Anders Björkman,Andreas Mårtensson,José Pedro Gil,José Pedro Gil,José Pedro Gil +10 more
TL;DR: In this paper, the authors proposed a method to identify useful surveillance tools such as genetic markers of resistance against the long-acting partners in ACT, a clear definition of the P. falciparum resistance phenotype is needed.