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Irving F. Hoffman
Researcher at University of North Carolina at Chapel Hill
Publications - Â 288
Citations - Â 20382
Irving F. Hoffman is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 52, co-authored 270 publications receiving 18634 citations. Previous affiliations of Irving F. Hoffman include Kamuzu Central Hospital & FHI 360.
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A scalable, integrated intervention to engage people who inject drugs in HIV care and medication-assisted treatment (HPTN 074): a randomised, controlled phase 3 feasibility and efficacy study.
William C. Miller,Irving F. Hoffman,Brett Hanscom,Tran Viet Ha,Kostyantyn Dumchev,Zubairi Djoerban,Scott Rose,Carl A. Latkin,David S. Metzger,Kathryn E. Lancaster,Vivian F. Go,Sergii Dvoriak,Katie R. Mollan,Sarah A. Reifeis,Estelle Piwowar-Manning,Paul G. Richardson,Michael G. Hudgens,Erica L. Hamilton,Jeremy Sugarman,Susan H. Eshleman,Hepa Susami,Viet Anh Chu,Samsuridjal Djauzi,Tetiana Kiriazova,Duong D Bui,Steffanie A. Strathdee,David N. Burns +26 more
TL;DR: Evidence is provided that a flexible, scalable intervention increases ART and MAT use and reduces mortality among PWID and the feasibility of a future randomised controlled trial is assessed.
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A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmission.
Taha E. Taha,Elizabeth R. Brown,Elizabeth R. Brown,Irving F. Hoffman,Wafaie W. Fawzi,Jennifer S. Read,Moses Sinkala,Moses Sinkala,Francis Martinson,George Kafulafula,Gernard I. Msamanga,Lynda Emel,Samuel Adeniyi-Jones,Robert L. Goldenberg +13 more
TL;DR: This simple antepartum and peripartum antibiotic regimen did not reduce the risk of mother-to-child transmission (MTCT) of HIV-1.
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Modifications of a large HIV prevention clinical trial to fit changing realities: A case study of the Breastfeeding, Antiretroviral, and Nutrition (BAN) Protocol in Lilongwe, Malawi
Charles van der Horst,Charles Chasela,Yusuf Ahmed,Irving F. Hoffman,Mina C. Hosseinipour,Rodney J. Knight,Susan A. Fiscus,Michael G. Hudgens,Peter N. Kazembe,Peter N. Kazembe,Margaret E. Bentley,Linda S. Adair,Ellen G. Piwoz,Francis Martinson,Ann Duerr,Athena P. Kourtis,A. Edde Loeliger,Beth C. Tohill,Sascha R. Ellington,Denise J. Jamieson +19 more
TL;DR: The process of designing, implementing, and subsequently modifying the Breastfeeding, Antiretrovirals, and Nutrition, (BAN) Study, a large, on-going, randomized breastfeeding intervention trial of HIV-infected women and their infants conducted at a single-site in Lilongwe, Malawi is described.
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Genital Ulcers: Etiology, Clinical Diagnosis, and Associated Human Immunodeficiency Virus Infection in Kingston, Jamaica
Frieda Behets,Brathwaite A,Tina Hylton-Kong,Cheng-Yen Chen,Irving F. Hoffman,J. B. Weiss,Stephen A. Morse,Gina Dallabetta,Myron S. Cohen,Figueroa Jp +9 more
TL;DR: The relatively poor accuracy of clinical and locally available laboratory diagnoses pleads for syndromic management of genital ulcers in Jamaica and prevention efforts should be intensified.
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Use of Massively Parallel Pyrosequencing to Evaluate the Diversity of and Selection on Plasmodium falciparum csp T-Cell Epitopes in Lilongwe, Malawi
Jeffrey A. Bailey,Tisungane Mvalo,Nagesh Aragam,Matthew Weiser,Seth Congdon,Debbie Kamwendo,Francis Martinson,Irving F. Hoffman,Steven R. Meshnick,Jonathan J. Juliano +9 more
TL;DR: Evaluating the diversity of CS haplotypes across the T-cell epitopes in parasites from Lilongwe, Malawi saw evidence of weak variant-specific selection within this region of CS, suggesting naturally acquired immunity does induce variant- specific selection on CS.