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Irwin C. Gunsalus
Researcher at University of Illinois at Urbana–Champaign
Publications - 103
Citations - 13276
Irwin C. Gunsalus is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Cytochrome & Pseudomonas putida. The author has an hindex of 49, co-authored 103 publications receiving 13090 citations. Previous affiliations of Irwin C. Gunsalus include Scripps Health & Urbana University.
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Journal ArticleDOI
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
David R. Nelson,Luc Koymans,Tetsuya Kamataki,John J. Stegeman,Ren Feyereisen,David J. Waxman,Michael R. Waterman,Osamu Gotoh,Minor J. Coon,Ron W. Estabrook,Irwin C. Gunsalus,Daniel W. Nebert +11 more
TL;DR: This revision supersedes the four previous updates in which a nomenclature system, based on divergent evolution of the P450 superfamily has been described and is similar to that proposed in the previous updates.
Journal ArticleDOI
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.
David R. Nelson,Tetsuya Kamataki,David J. Waxman,F P Guengerich,Ronald W. Estabrook,René Feyereisen,Frank J. Gonzalez,Minor J. Coon,Irwin C. Gunsalus,Osamu Gotoh +9 more
TL;DR: The likelihood that this ancient gene superfamily has existed for more than 3.5 billion years, and that the rate of P450 gene evolution appears to be quite nonlinear, is discussed.
Journal ArticleDOI
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.
Daniel W. Nebert,David R. Nelson,Minor J. Coon,Ronald W. Estabrook,René Feyereisen,Yoshiaki Fujii-Kuriyama,Frank J. Gonzalez,F P Guengerich,Irwin C. Gunsalus,Eric F. Johnson +9 more
TL;DR: A modest revision of the initially proposed and updated and updated nomenclature system based on evolution of the superfamily P450 is proposed.
Journal ArticleDOI
The P450 gene superfamily: recommended nomenclature.
Daniel W. Nebert,Milton Adesnik,Minor J. Coon,Ronald W. Estabrook,Frank J. Gonzalez,F P Guengerich,Irwin C. Gunsalus,Eric F. Johnson,Byron Kemper,Wayne Levin +9 more
TL;DR: A nomenclature for the P450 gene superfamily is proposed based on evolution, and recommendations include Roman numerals for distinct gene families, capital letters for subfamilies, and Arabic numeral for individual genes.
Journal ArticleDOI
The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci
Daniel W. Nebert,David R. Nelson,Milton Adesnik,Minor J. Coon,Ronald W. Estabrook,Frank J. Gonzalez,F. Peter Guengerich,Irwin C. Gunsalus,Eric F. Johnson,Byron Kemper,Wayne Levin,Ian Phillips,Ryo Sato,Michael R. Waterman +13 more
TL;DR: A modest revision of the initially proposed nomenclature of the P450 superfamily is described specifically for the human and mouse chromosomal loci, with the root symbol "CYP" for human ("Cyp" for mouse), denoting "cytochrome P450."