Isabel Beets

TL;DR: This study presents a functional vasopressin- and oxytocin-like signaling system in the nematode Caenorhabditis elegans that facilitates the experience-driven modulation of salt chemotaxis, a type of gustatory associative learning in C. elegans, suggested to have ancient roles in modulating sensory processing in neural circuits that underlie behavioral plasticity.

TL;DR: The development of deorphanization strategies resulted in a significant increase in the knowledge of neuropeptidergic signaling in C. elegans, and complementary localization and functional studies demonstrate that neuropepeptides and their GPCRs represent a rich potential source of behavioral variability in the worm.

TL;DR: Neuropeptides are the largest class of neuromodulators in nervous systems and some of the challenges that remain for furthering the understanding of the functional relevance of peptidergic modulation are highlighted.

TL;DR: The roles of both NPF and sNPF systems in the regulation of feeding and metabolism in invertebrates are reviewed, indicating the functional importance of both.

TL;DR: The diversity, distribution, and functions of FLPs in nematodes are reviewed, including neuroendocrine and neuromodulatory effects on locomotory activity, reproduction, feeding, and behavior.