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Ishrat Mahjabeen
Researcher at COMSATS Institute of Information Technology
Publications - 65
Citations - 824
Ishrat Mahjabeen is an academic researcher from COMSATS Institute of Information Technology. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 15, co-authored 55 publications receiving 671 citations. Previous affiliations of Ishrat Mahjabeen include University of Illinois at Chicago.
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Down-regulation of the microRNA-99 family members in head and neck squamous cell carcinoma.
Zujian Chen,Yi Jin,Dongsheng Yu,Dongsheng Yu,Anxun Wang,Anxun Wang,Ishrat Mahjabeen,Ishrat Mahjabeen,Cheng Wang,Cheng Wang,Xiqiang Liu,Xiqiang Liu,Xiaofeng Zhou +12 more
TL;DR: The deregulation of miR-99 family contributes to the tumorigenesis of HNSCC, in part by targeting IGF1R and mTOR signaling pathways.
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Correlation between selected XRCC2, XRCC3 and RAD51 gene polymorphisms and primary breast cancer in women in Pakistan.
TL;DR: The results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymorphisms of XRCC3 and Arg188His polymorphismof XR CC2 can be independent markers of breast cancer risk in Pakistan.
miR-486-3p, miR-139-5p, and miR-21 as Biomarkers for the Detection of Oral Tongue Squamous Cell Carcinoma.
Zujian Chen,Tianwei Yu,Robert J. Cabay,Yi Jin,Ishrat Mahjabeen,Xianghong Luan,Lei Huang,Yang Dai,Xiaofeng Zhou +8 more
TL;DR: The feasibility of using microRNA biomarkers (miR-486-3p, miR-139-5p, andMiR-21) for the detection of TSCC was confirmed and the utility of the archived clinical specimens for micro RNA biomarker discovery was demonstrated.
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Mutational spectrum of Gelsolin and its down regulation is associated with breast cancer.
Ruqia Mehmood Baig,Ishrat Mahjabeen,Maimoona Sabir,Nosheen Masood,Kashif Ali,Faraz Arshad Malik,Mahmood Akhtar Kayani +6 more
TL;DR: It is concluded that genetic changes in coding regions of Gelsolin can potentially contribute to genetic instability and these genetic variations and expressional correlation with patient survival may prove to be of significant importance.
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Genetic and expressional variations of APEX1 are associated with increased risk of head and neck cancer.
TL;DR: This study demonstrated that AP EX1 mutations and deregulation of APEX1 are associated with increased risk of HNC in the Pakistani population.