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Ivanka Markovic

Researcher at University of Belgrade

Publications -  71
Citations -  8065

Ivanka Markovic is an academic researcher from University of Belgrade. The author has contributed to research in topics: Autophagy & Tiazofurin. The author has an hindex of 20, co-authored 63 publications receiving 7152 citations.

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Inhibition of mTOR-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic death.

TL;DR: The data suggest that the therapeutic efficiency of cytarabine in leukemic patients could be increased by the inhibition of the mTOR-dependent autophagic response.
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Isolation and biological evaluation of jatrophane diterpenoids from Euphorbia dendroides.

TL;DR: From the Montenegrin spurge Euphorbia dendroides, seven new diterpenoids were isolated and their structures elucidated by spectroscopic techniques, exerting a strong reversal potential resulting from inhibition of P-glycoprotein transport.
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Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R).

TL;DR: The results show that sulfinosine and curcumin overcome MDR in non-small cell lung carcinoma cell line (NSCLC), especially in combination despite the presence of a mutated p53 gene.
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Statin-mediated inhibition of cholesterol synthesis induces cytoprotective autophagy in human leukemic cells

TL;DR: Combined treatment with statins and autophagy inhibitors might be potentially useful in anti-leukemic therapy, and the inhibition of cholesterol synthesis was solely responsible for the induction of cytoprotective Autophagy.
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Jatrophane diterpenoids from the latex of Euphorbia dendroides and their anti-P-glycoprotein activity in human multi-drug resistant cancer cell lines

TL;DR: Jatrophanes 2 and 5 demonstrated the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR).