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Ivy L. Fowler
Researcher at GlaxoSmithKline
Publications - 7
Citations - 1148
Ivy L. Fowler is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Dutasteride & Prostate cancer. The author has an hindex of 5, co-authored 7 publications receiving 1067 citations. Previous affiliations of Ivy L. Fowler include Pharmaceutical Product Development.
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Journal ArticleDOI
Effect of dutasteride on the risk of prostate cancer.
Gerald L. Andriole,David G. Bostwick,Otis W. Brawley,Leonard G. Gomella,Michael Marberger,Francesco Montorsi,Curtis A. Pettaway,Teuvo L.J. Tammela,Claudio Teloken,Donald J. Tindall,Matthew C. Somerville,Timothy Wilson,Ivy L. Fowler,Roger S. Rittmaster +13 more
TL;DR: Over the course of the 4-year study period, dutasteride reduced the risk of incident prostate cancer detected on biopsy and improved the outcomes related to benign prostatic hyperplasia.
Journal ArticleDOI
The Effect of Dutasteride on the Usefulness of Prostate Specific Antigen for the Diagnosis of High Grade and Clinically Relevant Prostate Cancer in Men With a Previous Negative Biopsy: Results From the REDUCE Study
Gerald L. Andriole,David Bostwick,Otis W. Brawley,Leonard G. Gomella,Michael Marberger,Francesco Montorsi,Curtis A. Pettaway,Teuvo L.J. Tammela,Claudio Teloken,Donald J. Tindall,Stephen J. Freedland,Matthew C. Somerville,Timothy Wilson,Ivy L. Fowler,Ramiro Castro,Roger S. Rittmaster +15 more
TL;DR: In men with a previously negative prostate biopsy, prostate specific antigen performed better during the 4-year REDUCE study as a marker of prostate cancer in men who received dutasteride vs placebo.
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Biopsy Misidentification Identified by DNA Profiling in a Large Multicenter Trial
Michael Marberger,John D. McConnell,Ivy L. Fowler,Gerald L. Andriole,David G. Bostwick,Matthew C. Somerville,Roger S. Rittmaster +6 more
TL;DR: The potential for biopsy mismatches in clinical trials and clinical practice is an under-recognized problem that requires rigorous attention to details of chain of custody and consideration of more widespread DNA identity testing.
Journal ArticleDOI
Further analyses from the reduce prostate cancer risk reduction trial
Gerald L. Andriole,David Bostwick,Otis W. Brawley,Leonard G. Gomella,Michael Marberger,Francesco Montorsi,Curtis A. Pettaway,Teuvo L.J. Tammela,Claudio Teloken,Donald J. Tindall,Matthew C. Somerville,Ivy L. Fowler,Roger S. Rittmaster +12 more
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Comparison of Classic and International Society of Urological Pathology 2005 Modified Gleason grading using needle biopsies from the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial.
TL;DR: This analysis showed similar score distributions between the classic and modified Gleason scoring systems, and the differences seen between the 2 pathologists' scores likely reflect differences in interpretation rather than the scoring system chosen.