L
Leonard G. Gomella
Researcher at Thomas Jefferson University
Publications - 502
Citations - 18433
Leonard G. Gomella is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Prostate cancer & Prostatectomy. The author has an hindex of 70, co-authored 464 publications receiving 16715 citations. Previous affiliations of Leonard G. Gomella include Vanderbilt University Medical Center & University of Tampere.
Papers
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Journal ArticleDOI
Effect of dutasteride on the risk of prostate cancer.
Gerald L. Andriole,David G. Bostwick,Otis W. Brawley,Leonard G. Gomella,Michael Marberger,Francesco Montorsi,Curtis A. Pettaway,Teuvo L.J. Tammela,Claudio Teloken,Donald J. Tindall,Matthew C. Somerville,Timothy Wilson,Ivy L. Fowler,Roger S. Rittmaster +13 more
TL;DR: Over the course of the 4-year study period, dutasteride reduced the risk of incident prostate cancer detected on biopsy and improved the outcomes related to benign prostatic hyperplasia.
Journal ArticleDOI
Micro-RNA profiling in kidney and bladder cancers
Fedra Gottardo,Chang Gong Liu,Manuela Ferracin,George A. Calin,Matteo Fassan,Matteo Fassan,Pierfrancesco Bassi,Cinzia Sevignani,Dolores Byrne,Massimo Negrini,Francesco Pagano,Leonard G. Gomella,Carlo M. Croce,Raffaele Baffa +13 more
TL;DR: The role of micro-RNAs in the development and progression of kidney and bladder cancer was investigated in this paper, where the expression profiles of microRNAs were analyzed in kidney and urothelial carcinomas.
Journal ArticleDOI
MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets.
Raffaele Baffa,Matteo Fassan,Matteo Fassan,Stefano Volinia,Brian J. O'Hara,Chang Gong Liu,Juan P. Palazzo,Marina Paola Gardiman,Massimo Rugge,Leonard G. Gomella,Carlo M. Croce,Anne L. Rosenberg +11 more
TL;DR: The results suggest that specific miRNAs may be directly involved in cancer metastasis and that they may represent a novel diagnostic tool in the characterization of metastatic cancer gene targets.
Journal Article
Detection of hematogenous micrometastasis in patients with prostate cancer
Jose G. Moreno,Carlo M. Croce,Rainer Fischer,Maria Monne,P Vihko,Mulholland Sg,Leonard G. Gomella +6 more
TL;DR: Contrary to a long held hypothesis, these data point to the possibility that hematogenous metastasis may be a relatively early event in the natural history of human prostate cancer.
Journal ArticleDOI
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs
Eric Londina,Phillipe Lohera,Aristeidis G. Telonis,Kevin Quann,Peter Clark,Yi Jinga,Eleftheria Hatzimichael,Eleftheria Hatzimichael,Yohei Kirino,Shozo Honda,Michelle Lally,Bharat Ramratnam,Clay E.S. Comstock,Karen E. Knudsen,Leonard G. Gomella,George L Spaeth,Lisa A Hark,L. Jay Katz,Agnieszka K. Witkiewicz,Abdolmohamad Rostami,Sergio A. Jimenez,Michael A. Hollingsworth,Jen Jen Yeh,Chad A. Shaw,Steven E. McKenzie,Paul F. Bray,Peter T. Nelson,Simona Zupo,Katrien Van Roosbroeck,Michael J. Keating,Georg A. Calin,Charles J. Yeo,Masaya Jimbo,Joseph A. Cozzitorto,Jonathan R. Brody,Kathleen Delgrosso,John S. Mattick,John S. Mattick,Paolo Fortina,Isidore Rigoutsos +39 more
TL;DR: The findings suggest that the repertoire of human miRNAs is far more extensive than currently represented by public repositories and that there is a significant number of lineage- and/or tissue-specific mi RNAs that are uncharacterized.