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Iwona Cichon

Researcher at Jagiellonian University

Publications -  10
Citations -  329

Iwona Cichon is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Neutrophil extracellular traps & Inflammation. The author has an hindex of 4, co-authored 9 publications receiving 196 citations.

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To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

Sebastian Boeltz, +53 more
TL;DR: In this paper, the authors present prevailing concepts and state of the science in neutrophil extracellular traps (NET) related research and elaborate on open questions and areas of dispute.
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Scrutinizing Mechanisms of the ‘Obesity Paradox in Sepsis’: Obesity Is Accompanied by Diminished Formation of Neutrophil Extracellular Traps (NETs) Due to Restricted Neutrophil–Platelet Interactions

TL;DR: In this paper, the authors showed that neutrophil extracellular trap (NET) formation in liver vasculature is negligible in obese mice in sharp contrast to their lean counterparts (ND).
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Challenges in 3D culturing of neutrophils: Assessment of cell viability.

TL;DR: This work describes measures taken to establish a neutrophil-like cell line (nHL-60) and selection of 3D scaffolds (PuraMatrix alone or enriched with collagen type I) for their culturing and suggests application of resazurin, rather than tetrazolium-based dyes or trypan blue exclusion, for evaluation of neutrophils viability.
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Reduced Neutrophil Extracellular Trap (NET) Formation During Systemic Inflammation in Mice With Menkes Disease and Wilson Disease: Copper Requirement for NET Release.

TL;DR: Understanding on how microenvironmental factors affect NET release is extended by showing that copper is not a prerequisite for NET release but its excess affects the trap casting by neutrophils.