J
J Crowley
Researcher at University Hospital Galway
Publications - 33
Citations - 948
J Crowley is an academic researcher from University Hospital Galway. The author has contributed to research in topics: Stent & Gene delivery. The author has an hindex of 9, co-authored 27 publications receiving 667 citations. Previous affiliations of J Crowley include National University of Ireland, Galway & European Society of Cardiology.
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Journal ArticleDOI
Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry.
Kornelia Kotseva,Kornelia Kotseva,Guy De Backer,Guy De Backer,Dirk De Bacquer,Dirk De Bacquer,Lars Rydén,Lars Rydén,Arno W. Hoes,Arno W. Hoes,Diederick E. Grobbee,Diederick E. Grobbee,Aldo P. Maggioni,Pedro Marques-Vidal,Pedro Marques-Vidal,Catriona Jennings,Catriona Jennings,Ana Abreu,Carlos Aguiar,J. Badariene,Jan Bruthans,Jan Bruthans,Almudena Castro Conde,Renata Cifkova,Renata Cifkova,J Crowley,J Crowley,Kairat Davletov,Jaap W. Deckers,Jaap W. Deckers,Delphine De Smedt,Delphine De Smedt,Johan De Sutter,Johan De Sutter,Mirza Dilic,Mirza Dilic,Marina Dolzhenko,Vilnis Dzerve,Vilnis Dzerve,Andrejs Erglis,Andrejs Erglis,Zlatko Fras,Zlatko Fras,Zlatko Fras,Dan Gaita,Nina Gotcheva,Peter U. Heuschmann,Hosam Hasan-Ali,Piotr Jankowski,Nebojsa Lalic,Seppo Lehto,Dragan Lovic,S. Mancas,Linda Mellbin,Linda Mellbin,Davor Milicic,Davor Milicic,Erkin M. Mirrakhimov,Erkin M. Mirrakhimov,Rafael G. Oganov,Nana Pogosova,Zeljko Reiner,Zeljko Reiner,S Stoerk,Lâle Tokgözoğlu,Lâle Tokgözoğlu,Costas Tsioufis,Costas Tsioufis,Dusko Vulic,David R. Wood,David R. Wood,David R. Wood +71 more
TL;DR: A large majority of coronary patients have unhealthy lifestyles in terms of smoking, diet and sedentary behaviour, which adversely impacts major cardiovascular risk factors, and a majority did not achieve their blood pressure, low-density lipoprotein cholesterol and glucose targets.
Journal ArticleDOI
Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis.
Faisal Sharif,Sean O. Hynes,Ronan Cooney,Linda Howard,Jill McMahon,Kieran Daly,J Crowley,Frank Barry,Timothy O'Brien +8 more
TL;DR: Stent-based delivery of AdeNOS results in enhanced endothelial regeneration and reduction in neointimal formation as compared with controls and seems to be a promising treatment strategy for preventing in-stent restenosis (ISR) while simultaneously reducing the risk of stent thrombosis.
Journal ArticleDOI
Multiple source surveillance incidence and aetiology of out-of-hospital sudden cardiac death in a rural population in the West of Ireland.
TL;DR: The burden of SCD in the West of Ireland is considerable and the vast majority of cases occur in the home, where survival rates in this rural population cohort remain low.
Journal ArticleDOI
Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo.
Faisal Sharif,Sean O. Hynes,Jill McMahon,Ronan Cooney,Siobhan Conroy,Peter Dockery,Garry P. Duffy,Kieran Daly,J Crowley,Jeffrey S. Bartlett,Timothy O'Brien +10 more
TL;DR: Adeno-associated virus type 2 (AAV2) and adenovirus- and AAV2-coated stents can be used to deliver genes to the blood vessel wall for up to 28 days, using stents as delivery platforms.
Journal ArticleDOI
Gene-eluting stents: non-viral, liposome-based gene delivery of eNOS to the blood vessel wall in vivo results in enhanced endothelialization but does not reduce restenosis in a hypercholesterolemic model
Faisal Sharif,Faisal Sharif,Sean O. Hynes,Sean O. Hynes,Karl J. A. McCullagh,S Ganley,Udo Greiser,Peter E. McHugh,J Crowley,Frank Barry,Timothy O'Brien,Timothy O'Brien +11 more
TL;DR: It is shown that adenoviral endothelial nitric oxide synthase (eNOS) delivery can result in significantly decreased neointimal formation and enhanced re-endothelialization and liposomal eNOS delivery does not reduce restenosis rates.