J
J. Donald Easton
Researcher at University of California, San Francisco
Publications - 113
Citations - 22677
J. Donald Easton is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Stroke & Aspirin. The author has an hindex of 42, co-authored 104 publications receiving 20175 citations. Previous affiliations of J. Donald Easton include Brown University & Stanford University.
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Journal ArticleDOI
Transient Ischemic Attack — Proposal for a New Definition
Gregory W. Albers,Louis R. Caplan,J. Donald Easton,Pierre B. Fayad,J. P. Mohr,Jeffrey L. Saver,David G. Sherman +6 more
TL;DR: The definition of transient ischemic attack (TIA) and the assumptions underlying the definition have been out of date for some time and are no longer consistent with current concepts of brain ischemia.
Journal ArticleDOI
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
S. Claiborne Johnston,J. Donald Easton,Mary Farrant,William G. Barsan,Robin Conwit,Jordan J. Elm,Anthony S. Kim,Anne S. Lindblad,Yuko Y. Palesch +8 more
TL;DR: In patients with minor isChemic stroke or high‐risk TIA, those who received a combination of clopidogrel and aspirin had a lower risk of major ischemic events but a higher risk ofMajor hemorrhage at 90 days than those who receive aspirin alone.
Journal ArticleDOI
Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial
Deepak L. Bhatt,Marcus Flather,Werner Hacke,Peter B. Berger,Henry R. Black,William E. Boden,Patrice Cacoub,Eric A. Cohen,Mark A. Creager,J. Donald Easton,Christian W. Hamm,Graeme J. Hankey,S. Claiborne Johnston,Koon-Hou Mak,Jean-Louis Mas,Gilles Montalescot,Thomas A. Pearson,P. Gabriel Steg,Steven R. Steinhubl,Michael A. Weber,Liz Fabry-Ribaudo,Tingfei Hu,Eric J. Topol,Keith A.A. Fox,Charisma Investigators +24 more
TL;DR: In this analysis of the CHARISMA trial, the large number of patients with documented prior MI, ischemic stroke, or symptomatic PAD appeared to derive significant benefit from dual antiplatelet therapy with clopidogrel plus aspirin.
Journal ArticleDOI
Antithrombotic and thrombolytic therapy for ischemic stroke.
TL;DR: The key recommendations in this chapter are the following: for patients with acute ischemic stroke, administration of IV tissue plasminogen activator (tPA) if treatment is initiated within 3 h of clearly defined symptom onset (Grade 1A).
Journal ArticleDOI
Critical issues in peripheral arterial disease detection and management: a call to action.
Jill J. F. Belch,Eric J. Topol,Giancarlo Agnelli,Michel Bertrand,Robert M. Califf,Denis Clement,Mark A. Creager,J. Donald Easton,James R. Gavin,Philip Greenland,Graeme J. Hankey,Peter Hanrath,Alan T. Hirsch,Jürgen Meyer,Sidney C. Smith,Frank Sullivan,Michael A. Weber +16 more
TL;DR: This research presents a novel and scalable approach to understanding and treating atherothrombotic disease through a probabilistic approach called “informed consent” that combines natural selection, informed consent, and data collection and analysis.