J
J.P. Pignon
Researcher at Institut Gustave Roussy
Publications - 104
Citations - 13610
J.P. Pignon is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Lung cancer & non-small cell lung cancer (NSCLC). The author has an hindex of 36, co-authored 104 publications receiving 12896 citations. Previous affiliations of J.P. Pignon include Université Paris-Saclay.
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Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data
TL;DR: For larynx preservation, the non-significant negative effect of chemotherapy in the organ-preservation strategy indicates that this procedure must remain investigational and the routine use of chemotherapy is debatable.
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Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer.
Rodrigo Arriagada,Bengt Bergman,Ariane Dunant,Le Chevalier T,J.P. Pignon,Johan Vansteenkiste +5 more
TL;DR: Cisplatin-based adjuvant chemotherapy improves survival among patients with completely resected non-small-cell lung cancer and had a significantly higher survival rate than those assigned to observation.
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Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group.
Anne Auperin,Rodrigo Arriagada,J.P. Pignon,Le Péchoux C,A. Gregor,Richard Stephens,P. E.G. Kristjansen,B. E. Johnson,Hiroshi Ueoka,Henry N. Wagner,Joseph Aisner +10 more
TL;DR: Prophylactic cranial irradiation improves both overall survival and disease-free survival among patients with small-cell lung cancer in complete remission and identifies a trend toward a decrease in the risk of brain metastasis with earlier administration of cranials irradiation after the initiation of induction chemotherapy.
Journal ArticleDOI
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta analysis of chemotherapy on head and neck cancer
Journal ArticleDOI
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer.
Pascal Piedbois,Ph. Rougier,Marc Buyse,J.P. Pignon,Louise Ryan,R Hansen,Benny Zee,B Weinerman,J Pater,Cynthia G. Leichman,John S. Macdonald,Jacqueline Benedetti,J Lokich,J Fryer,G Brufman,R Isacson,Agnès Laplanche,E Levy +17 more
TL;DR: 5-FU CI is superior to 5-FU bolus in terms of tumor response and achieves a slight increase of overall survival, and the hematologic toxicity is much less important in patients who receive 5-fu CI, but hand-foot syndrome is frequent in this group of patients.