J
Jaap ten Oever
Researcher at Radboud University Nijmegen
Publications - 80
Citations - 2097
Jaap ten Oever is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 55 publications receiving 1216 citations. Previous affiliations of Jaap ten Oever include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections.
TL;DR: A model in which the inflammatory response to viral (IL-18/ferritin) and bacterial infections presents with specific plasma patterns of immune biomarkers is proposed.
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Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020.
Alma Tostmann,John S. Bradley,Teun Bousema,Teun Bousema,Wing-Kee Yiek,Minke Holwerda,Chantal P. Bleeker-Rovers,Jaap ten Oever,Corianne Meijer,Janette Rahamat-Langendoen,Joost Hopman,Nannet van der Geest-Blankert,Heiman F. L. Wertheim +12 more
TL;DR: Predictive models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, but they can contribute to targeted screening strategies.
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Healthcare-associated prosthetic heart valve, aortic vascular graft, and disseminated Mycobacterium chimaera infections subsequent to open heart surgery.
Philipp Kohler,Stefan P. Kuster,Guido V. Bloemberg,Bettina Schulthess,Michelle Frank,Felix C. Tanner,Matthias Rössle,Christian Böni,Volkmar Falk,Markus J. Wilhelm,Rami Sommerstein,Yvonne Achermann,Jaap ten Oever,Sylvia B. Debast,Maurice J H M Wolfhagen,George J Brandon Bravo Bruinsma,Margreet C. Vos,Ad J.J.C. Bogers,Annerose Serr,Friedhelm Beyersdorf,Hugo Sax,Erik C. Böttger,Rainer Weber,Jakko van Ingen,Dirk Wagner,Barbara Hasse +25 more
TL;DR: Clinical aspects and treatment course of Mycobacterium chimaera infections subsequent to open-heart surgery and outcome is poor despite long-term antimycobacterial therapy, probably because biofilm formation hinders eradication of pathogens.
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Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study
Jakko van Ingen,Thomas Kohl,Katharina Kranzer,Barbara Hasse,Peter M. Keller,Anna K. Szafrańska,Doris Hillemann,Meera Chand,Meera Chand,Meera Chand,Peter W Schreiber,Rami Sommerstein,Rami Sommerstein,Christoph Berger,Michele Genoni,Christian Rüegg,Nicolas Troillet,Andreas F. Widmer,Sören L. Becker,Sören L. Becker,Mathias Herrmann,Tim Eckmanns,Sebastian Haller,Christiane Höller,Sylvia B. Debast,Maurice J H M Wolfhagen,Joost Hopman,Jan Kluytmans,Merel Langelaar,Daan W. Notermans,Jaap ten Oever,Peter van den Barselaar,Alexander B.A. Vonk,Margreet C. Vos,Nada Ahmed,Tim Brown,Derrick W. Crook,Derrick W. Crook,Theresa Lamagni,Nick Phin,E. Grace Smith,Maria Zambon,Annerose Serr,Tim Götting,W. Ebner,Alexander Thürmer,Christian Utpatel,Cathrin Spröer,Boyke Bunk,Ulrich Nübel,Guido V. Bloemberg,Erik C. Böttger,Stefan Niemann,Dirk Wagner,Hugo Sax +54 more
TL;DR: HCU contamination with M chimaera at the LivaNova factory seems a likely source for cardiothoracic surgery-related severe M chimeera infections diagnosed in Switzerland, Germany, the Netherlands, the UK, the USA, and Australia.
Journal ArticleDOI
Few bacterial co-infections but frequent empiric antibiotic use in the early phase of hospitalized patients with COVID-19: results from a multicentre retrospective cohort study in The Netherlands.
Zara Karami,Bram T Knoop,Anton S M Dofferhoff,Marc Blaauw,Nico A F Janssen,Marjan van Apeldoorn,Angèle P.M. Kerckhoffs,Josephine van de Maat,Jacobien Hoogerwerf,Jaap ten Oever +9 more
TL;DR: On presentation to the hospital bacterial co-infections are rare, while empiric antibiotics use is abundant, which implies that in patients with COVID-19 empiric antibiotic should be withheld, which has the potential to dramatically reduce the current overuse of antibiotics in the CO VID-19 pandemic.