J
Jackson Kirkman-Brown
Researcher at University of Birmingham
Publications - 78
Citations - 4114
Jackson Kirkman-Brown is an academic researcher from University of Birmingham. The author has contributed to research in topics: Sperm & Acrosome reaction. The author has an hindex of 31, co-authored 73 publications receiving 3528 citations. Previous affiliations of Jackson Kirkman-Brown include University of Massachusetts Medical School & Boston Children's Hospital.
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Journal ArticleDOI
The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
Lynne Robinson,Ioannis D. Gallos,Sarah J. Conner,Madhurima Rajkhowa,David Miller,Sheena E.M. Lewis,Jackson Kirkman-Brown,Arri Coomarasamy +7 more
TL;DR: The use of methods which select sperm without DNA damage for use in assisted conception treatment may reduce the risk of miscarriage, indicating that assays detecting DNA damage could be considered in those suffering from recurrent pregnancy loss.
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Mammalian Sperm Motility: Observation and Theory
Eamonn A. Gaffney,Hermes Gadêlha,Hermes Gadêlha,David J. Smith,David J. Smith,John Blake,Jackson Kirkman-Brown +6 more
TL;DR: The biological structure of the motile sperm appendage, the flagellum, is described and placed in the context of the mechanics underlying the migration of mammalian sperm through the numerous environments of the female reproductive tract.
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Human spermatozoa migration in microchannels reveals boundary-following navigation.
TL;DR: The behavior of migrating sperm in assorted microchannel geometries is examined to elucidate individual and group behaviors that may occur in the complex three-dimensional female tract environment and to accounted for in future in vitro studies of sperm chemoattraction.
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Human sperm accumulation near surfaces: a simulation study
TL;DR: In this article, a hybrid boundary integral/slender body algorithm for modelling flagellar cell motility is presented, which is used to investigate the mechanisms for the accumulation of human spermatozoa near surfaces.
Journal ArticleDOI
Bend propagation in the flagella of migrating human sperm, and its modulation by viscosity.
David J. Smith,Eamonn A. Gaffney,Hermes Gadêlha,Hermes Gadêlha,N Kapur,Jackson Kirkman-Brown +5 more
TL;DR: High frame rate digital imaging is used for the first time to characterise the flagellar movement of migrating sperm in low and high viscosities, and shows in precise spatial and temporal detail waveform evolution along theFlagellum.