Institution
Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior
About: Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior is a based out in . It is known for research contribution in the topics: Population & Context (language use). The organization has 1531 authors who have published 1934 publications receiving 34534 citations.
Topics: Population, Context (language use), Gene, Species richness, Galaxy
Papers published on a yearly basis
Papers
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TL;DR: In this brief review, the evidence of seafood contamination by microplastics is reviewed, and the potential consequences of the presence of microplastic in the marine environment for human food security, food safety and health are discussed.
822 citations
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University of Grenoble1, Centre national de la recherche scientifique2, Austral University of Chile3, Queen's University4, Universidade Federal do Rio Grande do Sul5, Universidade Federal de Goiás6, Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior7, State University of Campinas8, Academy of Sciences of the Czech Republic9, Sewanee: The University of the South10, Federal University of Rio Grande do Norte11, University of Montpellier12, Swedish University of Agricultural Sciences13, Institut national de la recherche agronomique14, Tohoku University15, United Nations University16, University of Florida17, Université du Québec à Montréal18, University of Maryland, College Park19, Université de Sherbrooke20, Landcare Research21, Spanish National Research Council22, Lund University23, University of Tokyo24, Algoma University25, Umeå University26, Natural History Museum27
TL;DR: This paper conducted a meta-analysis of the relative extent of ITV within and among plant communities worldwide, using a data set encompassing 629 communities (plots) and 36 functional traits.
Abstract: Recent studies have shown that accounting for intraspecific trait variation (ITV) may better address major questions in community ecology. However, a general picture of the relative extent of ITV compared to interspecific trait variation in plant communities is still missing. Here, we conducted a meta-analysis of the relative extent of ITV within and among plant communities worldwide, using a data set encompassing 629 communities (plots) and 36 functional traits. Overall, ITV accounted for 25% of the total trait variation within communities and 32% of the total trait variation among communities on average. The relative extent of ITV tended to be greater for whole-plant (e.g. plant height) vs. organ-level traits and for leaf chemical (e.g. leaf N and P concentration) vs. leaf morphological (e.g. leaf area and thickness) traits. The relative amount of ITV decreased with increasing species richness and spatial extent, but did not vary with plant growth form or climate. These results highlight global patterns in the relative importance of ITV in plant communities, providing practical guidelines for when researchers should include ITV in trait-based community and ecosystem studies.
653 citations
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Bielefeld University1, University of Düsseldorf2, BRICS3, Oregon State University4, University of California, San Diego5, Aarhus University6, University of Copenhagen7, Roskilde University8, Joint Genome Institute9, Pittsburgh Supercomputing Center10, Saint Petersburg State University11, Max Planck Society12, University of Vienna13, University of Technology, Sydney14, Centre national de la recherche scientifique15, Genome Institute of Singapore16, University of Warwick17, University of Tübingen18, Intel19, French Institute for Research in Computer Science and Automation20, Taipei Medical University21, Joint BioEnergy Institute22, Lawrence Berkeley National Laboratory23, Georgia Institute of Technology24, University of Calgary25, University of Göttingen26, National Health Research Institutes27, San Diego State University28, Boyce Thompson Institute for Plant Research29, Robert Koch Institute30, Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior31, University of Maryland, College Park32, Newcastle University33, Leibniz Association34, ETH Zurich35
TL;DR: The Critical Assessment of Metagenome Interpretation (CAMI) challenge has engaged the global developer community to benchmark their programs on highly complex and realistic data sets, generated from ∼700 newly sequenced microorganisms and ∼600 novel viruses and plasmids and representing common experimental setups as discussed by the authors.
Abstract: Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome data, but a lack of consensus about benchmarking complicates performance assessment. The Critical Assessment of Metagenome Interpretation (CAMI) challenge has engaged the global developer community to benchmark their programs on highly complex and realistic data sets, generated from ∼700 newly sequenced microorganisms and ∼600 novel viruses and plasmids and representing common experimental setups. Assembly and genome binning programs performed well for species represented by individual genomes but were substantially affected by the presence of related strains. Taxonomic profiling and binning programs were proficient at high taxonomic ranks, with a notable performance decrease below family level. Parameter settings markedly affected performance, underscoring their importance for program reproducibility. The CAMI results highlight current challenges but also provide a roadmap for software selection to answer specific research questions.
593 citations
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TL;DR: In this paper, the effects of in situ incubation time and particles size on the estimates of indigestible fractions of dry matter (iDM), neutral detergent fiber (iNDF), and acid detergent fibre (iADF) in cattle feeds and feces were evaluated.
Abstract: The aim of this work was to evaluate the effects of in situ incubation time and particles size on the estimates of indigestible fractions of dry matter (iDM), neutral detergent fiber (iNDF), and acid detergent fiber (iADF) in cattle feeds and feces. Samples of corn grain, wheat bran, corn silage, elephant grass, sugarcane, signal grass hay, corn straw, and feces obtained from cattle fed high and low concentrate diets were used. The samples were ground through 1 mm, 2 mm, and 3 mm screen sieve and put in 4 × 5 cm non-woven textile bags (20 mg DM/cm² of surface). The samples were divided in three groups, being each group incubated in the rumen of a crossbred heifer. The incubation procedure was conducted three times with the change of groups among animals. The following incubation times were used: 0, 12, 24, 48, 72, 96, 120, 144, 168, 192, 216, 240, and 312 hours. The contents of iDM, iNDF, and iADF were evaluated sequentially in each bag. The degradation profiles were interpreted by a non-linear logistic model. The particles size did not influence the estimates of iNDF and iADF. However, the particles size altered the rumen degradation dynamic rates of DM for corn silage and corn grain; of NDF for sugarcane, corn silage, and corn straw; and ADF for sugarcane. For those samples, the particle size has been positively associated with the incubation time necessary to estimate the indigestible fraction. Incubation times of 240 hours for DM and NDF, and 264 hours for ADF were suggested for obtaining more accurate estimates of indigestible fractions. The use of 2 mm particle size can increase the precision of estimates.
452 citations
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TL;DR: This review will consider the main types of dendrimer currently being explored and how they can be utilized as drug and gene carriers and functionalized to improve the delivery of cancer therapy.
Abstract: Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them promising structures for functionalization and also for conjugation with drugs and DNA/RNA. Their architecture, which can be controlled by different synthesis processes, allows the control of characteristics such as shape, size, charge, and solubility. Dendrimers have the ability to increase the solubility and bioavailability of hydrophobic drugs. The drugs can be entrapped in the intramolecular cavity of the dendrimers or conjugated to their functional groups at their surface. Nucleic acids usually form complexes with the positively charged surface of most cationic dendrimers and this approach has been extensively employed. The presence of functional groups in the dendrimer’s exterior also permits the addition of other moieties that can actively target certain diseases and improve delivery, for instance, with folate and antibodies, now widely used as tumor targeting strategies. Dendrimers have been investigated extensively in the medical field, and cancer treatment is one of the greatest areas where they have been most used. This review will consider the main types of dendrimer currently being explored and how they can be utilized as drug and gene carriers and functionalized to improve the delivery of cancer therapy.
441 citations
Authors
Showing all 1531 results
Name | H-index | Papers | Citations |
---|---|---|---|
Terence G. Langdon | 117 | 1158 | 61603 |
William J. Catalona | 106 | 585 | 46729 |
Alfredo Fusco | 97 | 550 | 35319 |
T. Ylinen | 77 | 106 | 24382 |
Arthur L. Burnett | 77 | 465 | 25067 |
David B. Pyne | 69 | 359 | 16265 |
Mariangela Hungria | 67 | 389 | 15219 |
José Alexandre de Souza Crippa | 66 | 406 | 16784 |
Phillipa Hay | 63 | 404 | 14398 |
Attilio Converti | 59 | 437 | 13431 |
Jaime Eduardo Cecílio Hallak | 59 | 354 | 12057 |
Fabian M. Jaksic | 54 | 232 | 9700 |
Ronaldo A. Ribeiro | 51 | 211 | 7709 |
Antonio Pinto | 50 | 276 | 9191 |
Sergio A. Navarrete | 49 | 142 | 8043 |