J
Jacqueline Cordell
Researcher at University of Oxford
Publications - 25
Citations - 4821
Jacqueline Cordell is an academic researcher from University of Oxford. The author has contributed to research in topics: Monoclonal antibody & Antibody. The author has an hindex of 17, co-authored 24 publications receiving 4769 citations. Previous affiliations of Jacqueline Cordell include John Radcliffe Hospital & Royal College of Surgeons in Ireland.
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Journal ArticleDOI
Detection of normal and chimeric nucleophosmin in human cells.
Jacqueline Cordell,Karen Pulford,Barbara Bigerna,Giovanna Roncador,Alison H. Banham,Emanuela Colombo,Pier Giuseppe Pelicci,David Y. Mason,Brunangelo Falini +8 more
TL;DR: Three new monoclonal antibodies are described, two of which recognize, by Western blotting, the N-terminal portion of NPM present in the N PM-ALK fusion protein and also in two other NPM fusion proteins (NPM-RARalpha and NPM-MLF1).
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Preparation of peroxidase: antiperoxidase (PAP) complexes for immunohistological labeling of monoclonal antibodies.
TL;DR: Gel filtration revealed that monoclonal PAP is of lower molecular weight than conventional PAP complexes (fulfilling theoretical predictions based on the monospecificity of monOClonal antibodies), and gave the best immunohistological labeling reactions.
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CD5 is associated with the human B cell antigen receptor complex.
A. C. Lankester,G. M. W. Van Schijndel,Jacqueline Cordell,C. J. M. Van Noesel,R. A. W. Van Lier +4 more
TL;DR: It is demonstrated that CD5 is associated with the B cell receptor (BCR) complex and serves as substrate for BCR‐induced tyrosine kinase activity, meaning CD5+ B cells have a unique potential to modulate BCR signals.
Journal Article
Sensitive detection of DNA modifications induced by cisplatin and carboplatin in vitro and in vivo using a monoclonal antibody.
Michael J. Tilby,Caroline H. Johnson,Richard J. Knox,Jacqueline Cordell,John J. Roberts,C. J. Dean +5 more
TL;DR: An assay that is based upon a monoclonal antibody (ICR4) is described that enables the quantitation of cisplatin-induced adducts on DNA down to 3 nmol Pt/g DNA, the level necessary to produce toxic effects in cells in vitro and in vivo, using just a few micrograms of DNA.
Journal ArticleDOI
The B29 and mb-1 polypeptides are differentially expressed during human B cell differentiation.
David Y. Mason,C. J. M. Van Noesel,Jacqueline Cordell,W. M. Comans-Bitter,K Micklem,A. G. D. Tse,R. A. W. Van Lier,J J M van Dongen +7 more
TL;DR: Results suggest that the synthesis of B29 begins later in precursor B cells than that of mb‐1, and ceases before the terminal plasmacyte phase, indicating that this component in man is also encoded by the B29 gene.