J
Jacqueline K. Barton
Researcher at California Institute of Technology
Publications - 430
Citations - 45235
Jacqueline K. Barton is an academic researcher from California Institute of Technology. The author has contributed to research in topics: DNA & Base pair. The author has an hindex of 100, co-authored 429 publications receiving 43349 citations. Previous affiliations of Jacqueline K. Barton include City University of New York & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
DNA Electrochemistry: Charge-Transport Pathways through DNA Films on Gold.
TL;DR: In this paper, the authors demonstrate DNA electrochemistry with a fully AT DNA sequence using a thiolated preformed DNA duplex and distinguish this DNA-mediated chemistry from single-stranded DNA adsorbed to the surface.
Journal ArticleDOI
Charge separation in a ruthenium-quencher conjugate bound to DNA.
TL;DR: transient absorption measurements reveal a novel photophysical reaction pathway for [{Ru(phen)(dppz)(bpy'-his)}{Ru(NH3)5}]5+ in the presence of DNA that is competitive with the intramolecular flash-quench process.
Journal ArticleDOI
A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.
TL;DR: A bimetallic complex derived from a new family of potent and selective metalloinsertors containing an unusual Rh-O axial coordination incorporates a monofunctional platinum center containing only one labile site for coordination to DNA, rather than two, and coordinates DNA nonclassically through adduct formation in the minor groove.
Book ChapterDOI
Radical migration through the DNA helix: chemistry at a distance.
TL;DR: Questions concerning charge migration through DNA arise that can now be addressed through well-defined chemical experiments and need to be addressed in the context of delineating mechanisms of DNA damage and repair.
Journal ArticleDOI
DNA recognition by metal-peptide complexes containing the recognition helix of the phage 434 repressor
TL;DR: Comparative cleavage studies on synthetic oligonucleotides containing variations in operator sequence reveal a hierarchy in sequence preference which resembles the native protein, but highest affinity for the metal-peptides, unlike 434R, is found for 5′-ACGA-3′.