J
Jacques Pépin
Researcher at Université de Sherbrooke
Publications - 166
Citations - 16920
Jacques Pépin is an academic researcher from Université de Sherbrooke. The author has contributed to research in topics: Population & Trypanosomiasis. The author has an hindex of 56, co-authored 163 publications receiving 16134 citations. Previous affiliations of Jacques Pépin include Centre Hospitalier Universitaire de Sherbrooke & University of Manitoba.
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Journal ArticleDOI
Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
Stuart H. Cohen,Dale N. Gerding,Stuart Johnson,Ciaran P. Kelly,Vivian G. Loo,L. Clifford McDonald,Jacques Pépin,Mark H. Wilcox +7 more
TL;DR: This guideline updates recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management of Clostridium difficile.
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Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
Michel Warny,Jacques Pépin,Aiqi Fang,George Killgore,Angela Thompson,Jon S. Brazier,Eric Frost,L. Clifford McDonald +7 more
TL;DR: The severity of C difficile-associated disease caused by NAP1/027 could result from hyperproduction of toxins A and B, and dissemination of this strain in North America and Europe could lead to important changes in the epidemiology of C diffusion disease.
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Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity
Jacques Pépin,Louis Valiquette,Marie-Eve Alary,Philippe Villemure,Annick Pelletier,Karine Forget,Karine Pépin,Daniel Chouinard +7 more
TL;DR: An epidemic of CDAD with an increased case-fatality rate has had important consequences on the elderly population of Quebec and the equivalence of vancomycin and metronidazole in the treatment ofCDAD needs to be questioned.
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Emergence of Fluoroquinolones as the Predominant Risk Factor for Clostridium difficile–Associated Diarrhea: A Cohort Study during an Epidemic in Quebec
Jacques Pépin,Nathalie Saheb,Marie-Andrée Coulombe,Marie-Eve Alary,Marie-Pier Corriveau,Simon Authier,Michel Leblanc,Geneviève Rivard,Mathieu Bettez,Valérie Primeau,Martin Nguyen,Claude-Émilie Jacob,Luc Lanthier +12 more
TL;DR: Administration of fluoroquinolones emerged as the most important risk factor for CDAD in Quebec during an epidemic caused by a hypervirulent strain of C. difficile.
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Mortality attributable to nosocomial Clostridium difficile–associated disease during an epidemic caused by a hypervirulent strain in Quebec
TL;DR: A high attributable mortality among elderly patients with CDAD mostly caused by a hypervirulent strain is documented, which represents a dramatic change in the severity of this infection.