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Eric Frost
Researcher at Université de Sherbrooke
Publications - 151
Citations - 8798
Eric Frost is an academic researcher from Université de Sherbrooke. The author has contributed to research in topics: Population & Chlamydia trachomatis. The author has an hindex of 42, co-authored 149 publications receiving 7777 citations. Previous affiliations of Eric Frost include University of Tokyo & Centre Hospitalier Universitaire de Sherbrooke.
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Journal ArticleDOI
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
Michel Warny,Jacques Pépin,Aiqi Fang,George Killgore,Angela Thompson,Jon S. Brazier,Eric Frost,L. Clifford McDonald +7 more
TL;DR: The severity of C difficile-associated disease caused by NAP1/027 could result from hyperproduction of toxins A and B, and dissemination of this strain in North America and Europe could lead to important changes in the epidemiology of C diffusion disease.
Journal ArticleDOI
Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?
Tamas Fulop,Anis Larbi,Gilles Dupuis,Aurélie Le Page,Eric Frost,Alan A. Cohen,Jacek M. Witkowski,Claudio Franceschi +7 more
TL;DR: Recent cumulative data suggest that, without the existence of the immunosenescence/inflamm-aging duo, human longevity would be greatly shortened and it may be more suitable to aim to maintain general homeostasis and function by appropriately improving immune-inflammatory-functions.
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Host and Pathogen Factors for Clostridium difficile Infection and Colonization
Vivian G. Loo,Anne-Marie Bourgault,Louise Poirier,François Lamothe,Sophie Michaud,Nathalie Turgeon,Baldwin Toye,Axelle Beaudoin,Eric Frost,Rodica Gilca,Paul Brassard,Nandini Dendukuri,Claire Béliveau,Matthew Oughton,Ivan Brukner,Andre Dascal +15 more
TL;DR: Health care-associated C. difficile infection and colonization were differentially associated with defined host and pathogen variables, whereas asymptomatic patients were more likely to be colonized with other strains.
Journal ArticleDOI
Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue.
TL;DR: Using this improved method, ts and hr mutations in intact DNA have been rescued with restriction endonuclease fragments of DNA bearing the corresponding wild-type genetic markers and a number of mutations have been located unequivocally within the left quarter of the genome.
Journal ArticleDOI
Comparison of Seven Techniques for Typing International Epidemic Strains of Clostridium difficile: Restriction Endonuclease Analysis, Pulsed-Field Gel Electrophoresis, PCR-Ribotyping, Multilocus Sequence Typing, Multilocus Variable-Number Tandem-Repeat Analysis, Amplified Fragment Length Polymorphism, and Surface Layer Protein A Gene Sequence Typing
George Killgore,Angela Thompson,Stuart Johnson,Jon S. Brazier,Ed J. Kuijper,Jacques Pépin,Eric Frost,Paul H. M. Savelkoul,Brad Nicholson,Renate J. van den Berg,Haru Kato,Susan P. Sambol,Walter Zukowski,Christopher W. Woods,Brandi Limbago,Dale N. Gerding,L. Clifford McDonald +16 more
TL;DR: All techniques appear to be capable of detecting outbreak strains, but only REA and MLVA showed sufficient discrimination to distinguish strains from different outbreaks.