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James F. Toole

Researcher at Wake Forest University

Publications -  208
Citations -  12270

James F. Toole is an academic researcher from Wake Forest University. The author has contributed to research in topics: Stroke & Cerebral infarction. The author has an hindex of 50, co-authored 208 publications receiving 11963 citations. Previous affiliations of James F. Toole include University of California, San Diego & University of North Carolina at Chapel Hill.

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Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial.

TL;DR: In this trial, moderate reduction of total homocysteine after nondisabling cerebral infarction had no effect on vascular outcomes during the 2 years of follow-up, and the consistent findings of an association of totalhomocysteines with vascular risk suggests that further exploration of the hypothesis is warranted and longer trials in different populations with elevated total homocrysteine may be necessary.
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Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis. A case-control study.

TL;DR: B-mode score is strongly, consistently, and independently associated with coronary artery disease in patients older than 50 and is at least as useful as well-known risk factors for identifying patients with coronary arteries disease.
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Guidelines for Carotid Endarterectomy A Multidisciplinary Consensus Statement From the Ad Hoc Committee, American Heart Association

TL;DR: The American Heart Association assembled a group of experts in a multidisciplinary consensus conference to develop this statement as discussed by the authors, and each expert presented a talk and provided the chairman with a summary statement, from these summary statements a document was developed and edited onsite to achieve consensus before final revision.
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The global burden of disease study: implications for neurology.

TL;DR: This study provides compelling evidence that one cannot assess the neurologic health status of a population by examining mortality statistics alone, and health ministries worldwide must prioritize neurologic disorders.