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Mark A. Espeland
Researcher at Wake Forest University
Publications - 487
Citations - 36318
Mark A. Espeland is an academic researcher from Wake Forest University. The author has contributed to research in topics: Medicine & Dementia. The author has an hindex of 80, co-authored 421 publications receiving 31879 citations. Previous affiliations of Mark A. Espeland include Baylor College of Medicine & National Institutes of Health.
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Journal ArticleDOI
Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
Valery T. Miller,John C. LaRosa,Vanessa M. Barnabei,Craig M. Kessler,Ginny Levin,Ann Smith-Roth,Margaret Griffin,Diane B. Stoy,Trudy L. Bush,Howard A. Zacur,David A. Foster,Jean Anderson,Alice McKenzie,Susan C. Miller,Peter D. Wood,Marcia L. Stefanick,Robert Marcus,Allison Akana,W. Leroy Heinrichs,Charlene Kirchner,Katherine A. O'Hanlan,Melissa Ruyle,Mary A. Sheehan,Howard L. Judd,Gail A. Greendale,Richard Bayalos,Kathy Lozano,Kathy Kawakami,Elizabeth Barrett-Connor,Robert Langer,Donna Kritz-Silverstein,Mary Lou Carrion-Petersen,Carmela Cavero,Helmut G. Schrott,Susan R. Johnson,Deborah A. Feddersen,Denise L. Krutzfeldt,Jo Ann Benda,Carl J. Pauerstein,Jose Trabal,Robert S. Schenken,Michael P. Stern,Mercedes Rodriguez-Sifuentes,Carann Easton,H B Wells,Mark A. Espeland,George Howard,Robert Byington,Claudine Legault,Sally A. Shumaker,Patricia E. Hogan,Don Hire,Carol Wasilauskas,Margaret K. James,Kathy Lane,Tim Terrell,Stephanie Reece,June J Pierce,Mary Snow,Susan Anthony,Irma Mebane-Sims,Paula T. Einhorn,Sally Hunsberger,Myron A. Waclawiw,Ken Lippel,Diane L. Lucas,Joel Verter,Sherry Jackson,Joseph Kelaghan,Jeffrey M. Perlman,Pam Wolf,Joan McGowan,Stephen Gordon,Stephen Heyse,Judith E. Fradkin,Sherry Sherman,Lot B. Page,Ann Sorenson,Barbara S. Hulka,Baruch A. Brody,Ronald T. Burkman,Robert P. Heaney,Ronald M. Krauss,Harold Roberts,Janet Wittes,Lawrence Riggs,Richard Moss,John J. Albers,Santica M. Marcovina,S. Edwin Fineberg,Russell P. Tracy,Maria J. Merino,Robert E. Scully,Virginia A. LiVolsi,Gerald Kessler +94 more
TL;DR: Estrogen alone or in combination with a progestin improves lipoproteins and lowers fibrinogen levels without detectable effects on postchallenge insulin or blood pressure and in women with a uterus, CEE with cyclic MP has the most favorable effect on HDL-C and no excess risk of endometrial hyperplasia.
Journal ArticleDOI
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.
Rena R. Wing,Paula Bolin,Frederick L. Brancati,George A. Bray,Jeanne M. Clark,Mace Coday,Richard S. Crow,Jeffrey M. Curtis,Caitlin Egan,Mark A. Espeland,Mary Evans,John P. Foreyt,Siran Ghazarian,Edward W. Gregg,Barbara Harrison,Helen P. Hazuda,James O. Hill,Edward S. Horton,S. Van Hubbard,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,Abbas E. Kitabchi,William C. Knowler,Cora E. Lewis,Barbara J. Maschak-Carey,Maria G. Montez,Anne Murillo,David M. Nathan,Jennifer Patricio,Anne L. Peters,Xavier Pi-Sunyer,Henry J. Pownall,David M. Reboussin,Judith G. Regensteiner,Amy D. Rickman,Donna H. Ryan,Monika M. Safford,Thomas A. Wadden,Lynne E. Wagenknecht,Delia Smith West,David F. Williamson,Susan Z. Yanovski +43 more
TL;DR: An intensive lifestyle intervention focusing on weight loss did not reduce the rate of cardiovascular events in overweight or obese adults with type 2 diabetes.
Journal ArticleDOI
Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes: One-Year Results of the Look AHEAD Trial
Mark A. Espeland,Xavier Pi-Sunyer,George L. Blackburn,Frederick L. Brancati,George A. Bray,Renee Bright,Jeanne M. Clark,Jeffrey M. Curtis,John P. Foreyt,Kathryn Graves,Steven M. Haffner,Barbara Harrison,James O. Hill,Edward S. Horton,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,David E. Kelley,Abbas E. Kitabchi,William C. Knowler,Cora E. Lewis,Barbara J. Maschak-Carey,Brenda Montgomery,David M. Nathan,Jennifer Patricio,Anne L. Peters,J. Bruce Redmon,Rebecca S. Reeves,Donna H. Ryan,Monika M. Safford,Brent Van Dorsten,Thomas A. Wadden,Lynne E. Wagenknecht,Jacqueline Wesche-Thobaben,Rena R. Wing,Susan Z. Yanovski +36 more
TL;DR: At 1 year, ILI resulted in clinically significant weight loss in people with type 2 diabetes and was associated with improved diabetes control and CVD risk factors and reduced medicine use in ILI versus DSE.
Journal ArticleDOI
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial.
Rena R. Wing,Judy Bahnson,George A. Bray,Jeanne M. Clark,Mace Coday,Caitlin Egan,Mark A. Espeland,John P. Foreyt,Edward W. Gregg,Valerie Goldman,Steven M. Haffner,Helen P. Hazuda,James O. Hill,Edward S. Horton,Van S. Hubbard,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,Tina Killean,Abbas E. Kitabchi,Cora E. Lewis,Cathy Manus,Barbara J. Maschak-Carey,Sara Michaels,Maria G. Montez,Brenda Montgomery,David M. Nathan,Jennifer Patricio,Anne L. Peters,Xavier Pi-Sunyer,Henry J. Pownall,David M. Reboussin,W. Jack Rejeski,Richard R. Rubin,Monika M. Safford,Tricia Skarphol,Brent Van Dorsten,Thomas A. Wadden,Lynne E. Wagenknecht,Jacqueline Wesche-Thobaben,Delia S. West,Donald A. Williamson,Susan Z. Yanovski +43 more
TL;DR: Intensive lifestyle intervention can produce sustained weight loss and improvements in fitness, glycemic control, and CVD risk factors in individuals with type 2 diabetes.
Journal ArticleDOI
Sodium Reduction and Weight Loss in the Treatment of Hypertension in Older Persons: A Randomized Controlled Trial of Nonpharmacologic Interventions in the Elderly (TONE)
Paul K. Whelton,Lawrence J. Appel,Mark A. Espeland,William B. Applegate,Walter H. Ettinger,John B. Kostis,Shiriki K. Kumanyika,Shiriki K. Kumanyika,Clifton R. Lacy,Karen C. Johnson,Steven Folmar,Jeffrey A. Cutler +11 more
TL;DR: Reduced sodium intake and weight loss constitute a feasible, effective, and safe nonpharmacologic therapy of hypertension in older persons.