James G. Evans

TL;DR: This work predicts 19 proteins to be important for the function of complex I (CI) of the electron transport chain and validate a subset of these predictions using RNAi, including C8orf38, which is shown to have an inherited mutation in a lethal, infantile CI deficiency.

TL;DR: In adipocytes, insulin induces plasma membrane translocation of FATPs from an intracellular perinuclear compartment to the plasma membrane, which may play an important role in energy homeostasis and metabolic disorders such as type 2 diabetes.

TL;DR: Because daughter podosomes and podosome cluster precursors are preferentially located at the leading edge, they may play a critical role in continually generating new sites of cell adhesion.

TL;DR: Spindle pole penetration into the bud activates mitotic exit, resulting in Tem1p and Cdc15p persistence at the dSPB to initiate the MEN signal cascade, and fluorescence recovery after photobleaching (FRAP) measurements revealedTem1p-GFP is dynamic at thedSPB in late anaphase.

TL;DR: It is found that initiation and elongation occur during separate developmental stages, thus permitting analysis of these two phases of replication in vivo, and the pre–replication complex component, double-parked protein/cell division cycle 10–dependent transcript 1, is not only necessary for proper MCM2–7 localization, but, unexpectedly, is present during elongation.