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James H. O'Keefe

Researcher at University of Missouri–Kansas City

Publications -  450
Citations -  24406

James H. O'Keefe is an academic researcher from University of Missouri–Kansas City. The author has contributed to research in topics: Coronary artery disease & Myocardial infarction. The author has an hindex of 66, co-authored 432 publications receiving 21588 citations. Previous affiliations of James H. O'Keefe include University of Missouri & University of Kansas.

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Origins and evolution of the Western diet: health implications for the 21st century

TL;DR: The evolutionary collision of the authors' ancient genome with the nutritional qualities of recently introduced foods may underlie many of the chronic diseases of Western civilization.
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A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group.

TL;DR: As compared with t-PA therapy for acute myocardial infarction, immediate PTCA reduced the combined occurrence of nonfatal reinfarction or death, was associated with a lower rate of intracranial hemorrhage, and resulted in similar left ventricular systolic function.
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Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor?

TL;DR: A growing body of data suggests that low 25-hydroxyvitamin D levels may adversely affect cardiovascular health as discussed by the authors, and large randomized controlled trials are needed to firmly establish the relevance of vitamin D status to cardiovascular health.
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Exercise and the cardiovascular system: clinical science and cardiovascular outcomes

TL;DR: Data from epidemiological and ET studies in the primary and secondary prevention of cardiovascular diseases, particularly coronary heart disease and heart failure, strongly support the routine prescription of ET to all patients and referrals for patients with cardiovascular diseases to specific cardiac rehabilitation and ET programs.
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Postprandial Hyperglycemia/Hyperlipidemia (Postprandial Dysmetabolism) Is a Cardiovascular Risk Factor

TL;DR: The post-prandial dysmetabolism hypothesis has been bolstered by interventional studies that have demonstrated that blunting the post-andial spikes in glucose and lipids improves inflammation and endothelial function immediately as mentioned in this paper.