J
Jamie Case
Researcher at Scripps Health
Publications - 73
Citations - 2864
Jamie Case is an academic researcher from Scripps Health. The author has contributed to research in topics: Progenitor cell & CD34. The author has an hindex of 22, co-authored 72 publications receiving 2703 citations. Previous affiliations of Jamie Case include Indiana University – Purdue University Indianapolis & Boston Children's Hospital.
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Journal ArticleDOI
Human CD34+AC133+VEGFR-2+ cells are not endothelial progenitor cells but distinct, primitive hematopoietic progenitors
Jamie Case,Laura E. Mead,Waylan K. Bessler,Daniel N. Prater,Hilary White,M. Reza Saadatzadeh,Janak R. Bhavsar,Mervin C. Yoder,Laura S. Haneline,David A. Ingram +9 more
TL;DR: It is found that CD34+AC133+VEGFR-2+ cells are HPCs that do not yield EC progeny, and the biological mechanism for their correlation with cardiovascular disease needs to be reexamined.
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Endothelial progenitor cells: identity defined?
TL;DR: The role of EPCs in vascular biology is still a subject of much discussion as discussed by the authors, however, the lack of a unique EPC marker, identification challenges related to the paucity of ECs in the circulation, and the important phenotypical and functional overlap between EPC, haematopoietic cells and mature ECs are discussed.
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Working hypothesis to redefine endothelial progenitor cells
TL;DR: This review will attempt to outline the definition of EPCs from some of the most widely cited published reports in an effort to provide a framework for understanding subsequent studies in this rapidly evolving field.
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Flow Cytometric Identification and Functional Characterization of Immature and Mature Circulating Endothelial Cells
TL;DR: Two populations of circulating endothelial cells, including the functionally characterized ECFC, are now identifiable in human cord blood and peripheral blood by PFC.
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Oxidative stress impairs endothelial progenitor cell function.
TL;DR: The various cell and flow-cytometric techniques used to define and isolate EPCs from circulating blood and the current human and mouse genetic data, which offer insights into redox control in EPC biology and angiogenesis are discussed.