J
Jamie Case
Researcher at Scripps Health
Publications - 73
Citations - 2864
Jamie Case is an academic researcher from Scripps Health. The author has contributed to research in topics: Progenitor cell & CD34. The author has an hindex of 22, co-authored 72 publications receiving 2703 citations. Previous affiliations of Jamie Case include Indiana University – Purdue University Indianapolis & Boston Children's Hospital.
Papers
More filters
Neurofibromin Deficient Myeloid Cells are Critical Mediators of Aneurysm Formation In Vivo
Fang Li,Brandon D. Downing,Lucy C. Smiley,Julie A. Mund,Matthew R. Distasi,Waylan K. Bessler,Kara N. Sarchet,Daniel M. Hinds,Lisa M. Kamendulis,Cynthia M. Hingtgen,Jamie Case,D. Wade Clapp,Simon J. Conway,Brian K. Stansfield,David A. Ingram +14 more
TL;DR: In this paper, the authors used an angiotensin II-induced aneurysm model to demonstrate that heterozygous inactivation of NF1 (Nf1+/−) enhanced vessel wall formation with myeloid cell infiltration and increased oxidative stress.
Journal ArticleDOI
Neurofibromin-Deficient Myeloid Cells Are Critical Mediators of Aneurysm Formation In Vivo
Fang Li,Brandon D. Downing,Lucy C. Smiley,Julie A. Mund,Matthew R. Distasi,Waylan K. Bessler,Kara N. Sarchet,Daniel M. Hinds,Lisa M. Kamendulis,Cynthia M. Hingtgen,Jamie Case,D. Wade Clapp,Simon J. Conway,Brian K. Stansfield,David A. Ingram +14 more
TL;DR: Genetic and pharmacological evidence is provided that Nf1+/– myeloid cells are the cellular triggers for aneurysm formation in a novel model of NF1 vasculopathy and provide a potential therapeutic target.
Journal ArticleDOI
Skeletal muscle-derived progenitor cells exhibit neural competence.
TL;DR: It is demonstrated that phenotypically homogenous skeletal muscle progenitor cells defined as Lin−CD45−CD117−CD90+ cells express neural stem cell markers and are responsive to neural induction signals.
Journal ArticleDOI
Application of TruGraf v1: A Novel Molecular Biomarker for Managing Kidney Transplant Recipients With Stable Renal Function.
Christopher L. Marsh,Sunil M. Kurian,James C. Rice,Thomas Whisenant,J. David,S. Rose,C. Schieve,D. Lee,Jamie Case,Bethany Barrick,V. R. Peddi,Roslyn B. Mannon,Richard J. Knight,D. Maluf,Didier A. Mandelbrot,A. Patel,John J. Friedewald,Michael Abecassis,M. R. First +18 more
TL;DR: TruGraf v1 testing can potentially avoid painful and risky invasive biopsies, reduce health care costs, and enable frequent assessment of patients with stable renal function to confirm the presence of immune quiescence in the peripheral blood.
Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans
Waylan K. Bessler,Farlyn Z. Hudson,Hanfang Zhang,Valerie Harris,Yusi Wang,Julie A. Mund,Brandon D. Downing,David A. Ingram,Jamie Case,David J. Fulton,Brian K. Stansfield +10 more
TL;DR: In this article, the authors used compound mutant and lineage-restricted mice to demonstrate that Nf1(+/-) macrophages produce excessive reactive oxygen species (ROS) and enhance smooth muscle cell proliferation in vitro and in vivo.