Sunil M. Kurian

TL;DR: A major challenge for kidney transplantation is balancing the need for immunosuppression to prevent rejection, while minimizing drug‐induced toxicities.

TL;DR: At 2 years the sirolimus‐treated recipients have better renal function, a diminished prevalence of CAN and down‐regulated expression of genes responsible for progression of CAN, which may provide for an alternative natural history with improved graft survival.

TL;DR: The R function collapseRows is introduced that implements several collapsing methods and the function userListEnrichment is introduced, which assesses the enrichment of gene lists for known brain and blood cell type markers, and for other published biological pathways.

TL;DR: A predictive score developed based on a panel of 10 top candidate biomarkers shows sensitivity and specificity for high mood and low mood states, in two independent cohorts suggest that blood biomarkers may offer an unexpectedly informative window into brain functioning and disease state.

TL;DR: Predictive scores show good sensitivity and negative predictive value for detecting high psychosis states in the original cohort as well as in three additional cohorts, with implications for the development of objective laboratory tests to measure illness severity and response to treatment in devastating disorders such as schizophrenia.