J
Jan Borovicka
Researcher at University of St. Gallen
Publications - 65
Citations - 2868
Jan Borovicka is an academic researcher from University of St. Gallen. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 21, co-authored 48 publications receiving 2684 citations. Previous affiliations of Jan Borovicka include University of Zurich.
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Journal ArticleDOI
Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study
Andri Rauch,Zoltán Kutalik,Zoltán Kutalik,Patrick Descombes,Tao Cai,Julia di Iulio,Tobias Mueller,Murielle Bochud,Manuel Battegay,Enos Bernasconi,Jan Borovicka,Sara Colombo,Andreas Cerny,Jean-François Dufour,Hansjakob Furrer,Huldrych F. Günthard,Markus H. Heim,Bernard Hirschel,Raffaele Malinverni,Darius Moradpour,Beat Müllhaupt,Andrea Witteck,Jacques S. Beckmann,Jacques S. Beckmann,Thomas Berg,Sven Bergmann,Sven Bergmann,Francesco Negro,Amalio Telenti,Pierre-Yves Bochud +29 more
TL;DR: The association of the IL28B locus with natural and treatment-associated control of HCV indicates the importance of innate immunity and interferon lambda in the pathogenesis ofHCV infection.
Journal ArticleDOI
Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.
Pierre-Yves Bochud,Pierre-Yves Bochud,Tao Cai,Tao Cai,Kathrin Stéphanie Overbeck,Murielle Bochud,Jean-François Dufour,Beat Müllhaupt,Jan Borovicka,Markus H. Heim,Darius Moradpour,Andreas Cerny,Raffaele Malinverni,Patrick Francioli,Francesco Negro +14 more
TL;DR: This study shows a significant association of genotype 3 with accelerated fibrosis using both stage-constant and stage-specific estimates of fibrosis progression rates.
Journal ArticleDOI
Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease
Antonina Mikocka-Walus,Antonina Mikocka-Walus,Valérie Pittet,Jean-Benoît Rossel,Roland von Känel,Claudia Anderegg,Peter Bauerfeind,Christoph Beglinger,Stefan Begré,Dominique Charles Belli,José M. Bengoa,Luc Biedermann,Beat Bigler,Janek Binek,Mirjam Blattmann,Stephan Boehm,Jan Borovicka,Christian Braegger,Nora Brunner,Patrick Bühr,Bernard Burnand,Emanuel Burri,Sophie Buyse,Matthias Cremer,Dominique H. Criblez,Philippe de Saussure,Lukas Degen,Joakim Delarive,Christopher Doerig,Barbara Dora,Gian Dorta,Mara Egger,Tobias Ehmann,Ali El-Wafa,Matthias Engelmann,Jessica Ezri,Christian Felley,Markus Fliegner,Nicolas Fournier,Montserrat Fraga,Pascal Frei,Remus Frei,Michael Fried,Florian Froehlich,Christian Funk,Raoul I. Furlano,Suzanne Gallot-Lavallée,Martin Geyer,Marc Girardin,Delphine Golay,Tanja Grandinetti,Beat Gysi,Horst Haack,Johannes Haarer,Beat Helbling,Peter Hengstler,Denise Herzog,Cyrill Hess,Klaas Heyland,Thomas Hinterleitner,Philippe Hiroz,Claudia Hirschi,Petr Hruz,Rika Iwata,Res Jost,Pascal Juillerat,Vera Kessler Brondolo,Christina Knellwolf,Christoph Knoblauch,Henrik Köhler,Rebekka Koller,Claudia Krieger-Grübel,Gerd A. Kullak-Ublick,Patrizia Künzler,Markus A. Landolt,Rupprecht Lange,Frank Serge Lehmann,Andrew J. Macpherson,Philippe Maerten,Michel H. Maillard,Christine N. Manser,Michael Manz,Urs A. Marbet,George Marx,Christoph Matter,Valérie A. McLin,Rémy Meier,Martina Mendanova,Christa Meyenberger,Pierre Michetti,Benjamin Misselwitz,Darius Moradpour,Bernhard Morell,Patrick Mosler,Christian Mottet,Christoph Müller,Pascal Müller,Beat Müllhaupt,Claudia Münger-Beyeler,Leilla Musso,Andreas Nagy,Michaela Neagu,Cristina Nichita,Jan Niess,Natacha Noël,Andreas Nydegger,Nicole Obialo,Carl Oneta,Cassandra Oropesa,Ueli Peter,Daniel Peternac,Laëtitia Marie Petit,Franziska Piccoli-Gfeller,Julia Beatrice Pilz,Nadia Raschle,Ronald Rentsch,Sophie Restellini,Jean-Pierre Richterich,Sylvia Rihs,Marc Alain Ritz,Jocelyn Roduit,Daniela Rogler,Gerhard Rogler,Markus Sagmeister,Gaby Saner,Bernhard Sauter,Mikael Sawatzki,Michela Schäppi,Michael Scharl,Martin Schelling,Susanne Schibli,Hugo Schlauri,Sybille Schmid Uebelhart,Jean-François Schnegg,Alain M. Schoepfer,Frank Seibold,Mariam Seirafi,Gian-Marco Semadeni,David Semela,Arne Senning,Marc Sidler,Christiane Sokollik,Johannes Spalinger,Holger Spangenberger,Philippe Stadler,Michael Steuerwald,Alex Straumann,Bigna Straumann-Funk,Michael Christian Sulz,J. Thorens,Sarah Tiedemann,Radu Tutuian,Stephan R. Vavricka,Francesco Viani,Jürg Vögtlin,Alain Vonlaufen,Dominique Vouillamoz,Rachel Vulliamy,Jürg Wermuth,Helene Werner,P. Wiesel,Reiner Wiest,Tina Wylie,Jonas Zeitz,Dorothee Zimmermann +164 more
TL;DR: A significant association between symptoms of depression or anxiety and clinical recurrence of inflammatory bowel disease is found and patients with IBD should be screened for clinically relevant levels of depression and anxiety and referred to psychologists or psychiatrists for further evaluation and treatment.
Journal ArticleDOI
Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication
Donatella Ciuffreda,Denis Comte,Matthias Cavassini,Emiliano Giostra,Leo Buhler,Monika Perruchoud,Markus H. Heim,Manuel Battegay,Daniel Genné,Beat Mulhaupt,Raffaele Malinverni,Carl Oneta,Enos Bernasconi,Martine Monnat,Andreas Cerny,Christian Chuard,Jan Borovicka,Gilles Mentha,Manuel Pascual,J. J. Gonvers,Giuseppe Pantaleo,Valérie Dutoit +21 more
TL;DR: The present results suggest that immune‐based mechanisms may contribute to explain the accelerated course of HCV infection in conditions of HIV‐1 co‐infection and liver transplantation.
Journal ArticleDOI
Role of cholecystokinin in the regulation of liquid gastric emptying and gastric motility in humans: studies with the CCK antagonist loxiglumide
Werner Schwizer,Jan Borovicka,P Kunz,Robert J. Fraser,C Kreiss,M D'Amato,Gerard Crelier,Peter Boesiger,Michael Fried +8 more
TL;DR: The increases in antral motility are likely to contribute to the acceleration of GE and suggest that CCK may regulate GE by acting on the distal stomach although an effect on the proximal stomach cannot be excluded.