Janet Cox-Singh

TL;DR: The extent of polymorphism within the N‐terminal non‐repetitive region of the LSA‐1 gene from Malaysian P. falciparum field isolates was sequenced and compared with data of isolates from Brazil, Kenya and Papua New Guinea, and three of the T‐cell epitopes were completely conserved while the remaining two were highly conserved.

TL;DR: A static protein assay is used to determine if naturally occurring human P. knowlesi infections can cause erythrocytes to bind to ICAM-1, VCAM-2, and CD36, and to identify the receptors associated with PfEMP1.

TL;DR: A method to generate long-read third-generation Plasmodium genome sequence data from archived clinical samples using the MinION platform and it is proposed that by widely adopting this methodology important information on clinically relevant parasite diversity, including multiple gene family members, from geographically distinct study sites will emerge.

TL;DR: It is reported that the gp30 transcript is present in each of the life cycle stages, including mosquito derived L3's, and that there is a 50 fold increase in the transcription of gp30 in young adults (28 days post infection) compared to mature adults.

TL;DR: It is demonstrated that, in contrast to conserved core genes, SICAvar and kir genes occupy otherwise gene-sparse chromosomal locations that accommodate rapid evolution and change, and offers new insight into the complexity of clinically important real-world parasites.