J
Jasmine Parma
Researcher at Université libre de Bruxelles
Publications - 73
Citations - 6054
Jasmine Parma is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Thyroid & Thyrotropin receptor. The author has an hindex of 35, co-authored 73 publications receiving 5903 citations. Previous affiliations of Jasmine Parma include University of Mainz & Northwestern University.
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Journal ArticleDOI
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
Jasmine Parma,Laurence Duprez,Jacqueline Van Sande,Pascale Cochaux,Christine Gervy,J. Mockel,Jacques Emile Dumont,Gilbert Vassart +7 more
TL;DR: Somatic mutations in the carboxv-terminal portion of the third cytoplasmic loop of the thyrotropin receptor are identified in three out of eleven hyperfunctioning thyroid adenomas, showing that G-protein-coupled receptors are susceptible to constitutive activation by spontaneous somatic mutations and may thus behave as proto-oncogenes.
Journal ArticleDOI
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.
Rajiv D. Machado,Micheala A. Aldred,Victoria James,Rachel E. Harrison,Bhakti Patel,Edward C. Schwalbe,Ekkehard Gruenig,Bart Janssen,Rolf Koehler,Werner Seeger,Oliver Eickelberg,Horst Olschewski,C. Gregory Elliott,Eric W. Glissmeyer,John F. Carlquist,Miryoung Kim,Adam Torbicki,Anna Fijałkowska,Grzegorz Szewczyk,Jasmine Parma,Marc Abramowicz,Nazzareno Galiè,Hiroko Morisaki,Shingo Kyotani,Norifumi Nakanishi,Takayuki Morisaki,Marc Humbert,Gérald Simonneau,Olivier Sitbon,Florent Soubrier,Florence Coulet,Nicholas W. Morrell,Richard C. Trembath +32 more
TL;DR: In this paper, the authors present a compilation of data for 144 distinct mutations that alter the coding sequence of the BMPR2 gene identified in 210 independent pulmonary arterial hypertension (PAH) subjects.
Journal ArticleDOI
Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
Laurence Duprez,Jasmine Parma,Jacqueline Van Sande,A Allgeier,J Leclère,Claire Schvartz,Marie-Joëlle Delisle,Marc Decoulx,J. Orgiazzi,Jacques Emile Dumont,Gilbert Vassart +10 more
TL;DR: This new disease entity is the germline counterpart of hyperfunctioning thyroid adenomas, in which different somatic mutations with similar functional characteristics have been demonstrated.
Journal ArticleDOI
Familial Gestational Hyperthyroidism Caused by a Mutant Thyrotropin Receptor Hypersensitive to Human Chorionic Gonadotropin
Patrice Rodien,C. Bremont,M.-L. R. Sanson,Jasmine Parma,J. Van Sande,Sabine Costagliola,J. P. Luton,Gilbert Vassart,Laurence Duprez +8 more
TL;DR: Some degree of stimulation of the thyroid gland by human chorionic gonadotropin is common during early pregnancy, but overt hyperthyroidism may ensue when serum chorionics concentrations are abnormally high.
Journal ArticleDOI
Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene.
Peter Kopp,J. Van Sande,Jasmine Parma,L Duprez,H Gerber,E Joss,J L Jameson,Jacques Emile Dumont,Gilbert Vassart +8 more
TL;DR: A molecular basis for autonomous thyroid function has been found in some patients with hyperfunctioning thyroid adenomas, and somatic mutations in stimulatory G (guanine nucleotide–binding) have been found.