J
Jason Brown
Researcher at University of Regensburg
Publications - 5
Citations - 2405
Jason Brown is an academic researcher from University of Regensburg. The author has contributed to research in topics: Dentate gyrus & Olfactory bulb. The author has an hindex of 3, co-authored 3 publications receiving 2292 citations.
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Journal ArticleDOI
Transient expression of doublecortin during adult neurogenesis
Jason Brown,Sebastien Couillard-Despres,Christiana M. Cooper-Kuhn,Jürgen Winkler,Jürgen Winkler,Ludwig Aigner,H. Georg Kuhn +6 more
TL;DR: The transient expression pattern of DCX in neuronal committed progenitor cells/neuroblasts indicates that DCX could be developed into a suitable marker for adult neurogenesis and may provide an alternative to BrdU labeling.
Journal ArticleDOI
Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis.
Jason Brown,Christiana M. Cooper-Kuhn,Gerd Kempermann,Henriette van Praag,Henriette van Praag,Jürgen Winkler,Fred H. Gage,H. Georg Kuhn +7 more
TL;DR: The discrepancy between the olfactory bulb and the dentate gyrus suggests that these living conditions trigger locally through an as yet unidentified mechanism specific to neurogenic signals in the dentates gyrus.
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Impaired adult neurogenesis in mice lacking the transcription factor E2F1.
Christiana M. Cooper-Kuhn,Maurice Vroemen,Jason Brown,Hong Ye,Margaret A. Thompson,Jürgen Winkler,H. Georg Kuhn +6 more
TL;DR: It is demonstrated that the transcription factor E2F1, which is targeted by several signaling cascades that are activated by growth factors, is involved in neurogenesis in the adult brain.
Journal ArticleDOI
The Role of Nuclear Factor-Kappa B in Fibrinogen-Induced Inflammatory Responses in Cultured Primary Neurons
TL;DR: In this article , the authors found that Fibrinogen-induced gene expression of CCL2 and IL-6 and the expression of NF-κB protein were increased in response to a specific interaction of Fibulinogen with neurons.
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Vascular Effects on Cerebrovascular Permeability and Neurodegeneration
TL;DR: In this paper , the importance of changes in the BBB and possible mechanisms primarily involving fibrinogen in the development and/or progression of neuroinflammatory and neurodegenerative diseases resulting in memory decline is emphasized.