Javier Sanz-Fuentenebro

TL;DR: The data, although preliminary, suggest that clozapine may have a slightly superior efficacy in the initial year of treatment of first-episode treatment-naïve patients with schizophrenia, and this can be explained for the most part by greater adherence to this treatment.

TL;DR: A positive predictive role for cortical thinning in the frontal region with regard to clinical and cognitive improvement with clozapine and risperidone in FE patients with schizophrenia is supported.

TL;DR: In this paper, the authors reviewed the current medical evidence about the use of clozapine as a first-line treatment for naive first-episode psychosis patients, and found that the incidence and mortality of agranulocytosis could be lower than previously estimated and that all-cause mortality due to clozAPine is less than that associated to other antipsychotic drugs.

TL;DR: This study supports the existence of different cognitive subgroups within the psychoses with different neurobiological underpinnings as well as its relation with demographic, clinical and biological measurements.

TL;DR: Spectral entropy modulation with task performance is decreased in patients with schizophrenia and bipolar disorder, which might reflect a deficit in the synchronization of the neural assemblies that underlie cognitive activity.