J
Jaw Wen Chen
Researcher at Taipei Veterans General Hospital
Publications - 337
Citations - 11039
Jaw Wen Chen is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Coronary artery disease & Hazard ratio. The author has an hindex of 52, co-authored 313 publications receiving 9634 citations. Previous affiliations of Jaw Wen Chen include National Yang-Ming University & Johns Hopkins University.
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Journal ArticleDOI
High Glucose Impairs Early and Late Endothelial Progenitor Cells by Modifying Nitric Oxide–Related but Not Oxidative Stress–Mediated Mechanisms
Yung Hsiang Chen,Shing Jong Lin,Feng Yen Lin,Tao Cheng Wu,Chen Rong Tsao,Po Hsun Huang,Po Len Liu,Yuh-Lien Chen,Jaw Wen Chen +8 more
TL;DR: High glucose impaired the proliferation and function of early and late EPCs, suggesting the role of NO-related rather than oxidative stress–mediated mechanisms in hyperglycemia-caused EPC downregulation.
Journal ArticleDOI
Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients
Ying Hwa Chen,Shing Jong Lin,Ming Wei Lin,Hui Ling Tsai,San San Kuo,Jaw Wen Chen,Min Ji Charng,Tao Cheng Wu,Lung Ching Chen,Philip Yu-An Ding,Wen-Harn Pan,Yuh-Shan Jou,Lee-Young Chau +12 more
TL;DR: Results imply that the length polymorphism in the HO-1 gene promoter modulate the transcription of the gene in vascular cells, suggesting type 2 diabetics carrying longer (GT)n repeats might have higher oxidative stress and increased susceptibility to the development of CAD.
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Regulation of Cardiomyocyte Apoptotic Signaling by Insulin-like Growth Factor I
TL;DR: The effects of IGF I on Bcl-2, Bax, caspase 3, DNA fragmentation, and cell survival in primary cardiomyocytes is defined and may help elucidate how IGF I modulates apoptotic signaling in cardiac muscle.
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Systemic immune‐inflammation index (SII) predicted clinical outcome in patients with coronary artery disease
Ya Ling Yang,Cheng Hsueh Wu,Pai Feng Hsu,Su Chan Chen,Shao Sung Huang,Wan Leong Chan,Shing Jong Lin,Chia Yu Chou,Jaw Wen Chen,Ju Pin Pan,Min Ji Charng,Ying Hwa Chen,Tao Cheng Wu,Tse Min Lu,Po Hsun Huang,Hao Min Cheng,Chin Chou Huang,Chin Chou Huang,Shih Hsien Sung,Yenn Jiang Lin,Hsin Bang Leu +20 more
TL;DR: This study examines the predictive value of a novel systemic immune‐inflammation index (SII, platelet × neutrophil/lymphocyte ratio) in coronary artery disease patients.
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Independent prognostic value of elevated high-sensitivity C-reactive protein in chronic heart failure
Wei Hsian Yin,Jaw Wen Chen,Jaw Wen Chen,Hsu Lung Jen,Meng Cheng Chiang,Wen Pin Huang,An Ning Feng,Mason Shing Young,Shing Jong Lin,Shing Jong Lin +9 more
TL;DR: Findings suggest that an elevated level of hsCRP is an independent predictor of prognosis in CHF and can provide additional prognostic information for the risk stratification and treatment in patients with chronic CHF.