Jean-Christophe Baret

TL;DR: In this paper, the authors compare the various approaches used to derive the basic electrowetting equation, which has been shown to be very reliable as long as the applied voltage is not too high.

TL;DR: This work presents a general ultrahigh-throughput screening platform using drop-based microfluidics that overcomes limitations and revolutionizes both the scale and speed of screening.

TL;DR: A theoretical model based on the Poisson distribution accurately predicted the observed enrichment values using the starting cell density (cells per droplet) and the ratio of active to inactive cells, and all of the recovered cells were the active strain.

TL;DR: In this article, a drop-based microfluidics-based screening platform using aqueous drops dispersed in oil as picoliter-volume reaction vessels was proposed to identify new mutants of the enzyme horseradish peroxidase.

TL;DR: Droplet-based microfluidic platforms in which cells are grown in aqueous microcompartments separated by an inert perfluorocarbon carrier oil are described, which should open the way for high-throughput, cell-based screening that can use >1000-fold smaller assay volumes and has approximately 500x higher throughput than conventional microtiter plate assays.