J
Jean-Claude Willer
Researcher at French Institute of Health and Medical Research
Publications - 61
Citations - 4418
Jean-Claude Willer is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Reflex & Diffuse noxious inhibitory control. The author has an hindex of 31, co-authored 61 publications receiving 4251 citations. Previous affiliations of Jean-Claude Willer include Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Psychophysical and electrophysiological approaches to the pain-relieving effects of heterotopic nociceptive stimuli.
TL;DR: The nociceptive flexion reflex (RIII reflex) and the concurrent subjective pain score elicited by right sural nerve stimulation at random intensities were studied in 10 healthy volunteers and a close relationship was found between the recruitment curves of the reflex and the pain score as a function of stimulus intensity.
Journal ArticleDOI
Restoration of normal motor control in Parkinson's disease during REM sleep
Valérie Cochen De Cock,Marie Vidailhet,Smaranda Leu,Antonio Texeira,Emmanuelle Apartis,Alexis Elbaz,Emmanuel Roze,Jean-Claude Willer,J.P. Derenne,Yves Agid,Isabelle Arnulf +10 more
TL;DR: The restored motor control during REM sleep suggests a transient 'levodopa-like' reestablishment of the basal ganglia loop and parkinsonism may disappear by REM sleep-related disjunction between pyramidal and extrapyramidal systems.
Journal Article
Diffuse noxious inhibitory controls (DNIC) in animals and in man.
TL;DR: In this article, it was shown that lesions of the following structures did not modify DNIC: Periaqueductal grey (PAG), Cuneiform nucleus, Parabrachial area, locus coeruleus/subcoeruleus, rostral ventromedial medulla (RVM), including Raphe Magnus, Gigantocellularis and Paragigantocelluleis nuclei.
Book ChapterDOI
Diffuse Noxious Inhibitory Controls (DNIC)
D. Le Bars,Jean-Claude Willer +1 more
TL;DR: This chapter summarizes experiments in both human beings and animals which show that diffuse noxious inhibitory controls (DNICs) are sustained by a well-defined neurological substratum based on spino-reticulo-spinal processes.
Journal ArticleDOI
Electromyography guides toward subgroups of mutations in muscle channelopathies
Emmanuel Fournier,Marianne Arzel,Damien Sternberg,Savine Vicart,Pascal Laforêt,Bruno Eymard,Jean-Claude Willer,Nacira Tabti,Bertrand Fontaine,Bertrand Fontaine +9 more
TL;DR: It is hypothesized that mutations are segregated into the different electromyographic patterns according to the underlying pathophysiological mechanisms and may be used in clinical practice as guides for molecular diagnosis of myotonia or periodic paralysis.